NCT04195815

Brief Summary

The investigators will assess the feasibility of activity monitoring armbands for continuous measurement of physical activity level in ME/CFS patients, during 6 months follow-up. The main purpose is to assess if continuous measurement of activity level may be incorporated in outcome measures in future clinical interventional trials.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
27

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 10, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 12, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

March 11, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 20, 2020

Completed
Last Updated

May 11, 2021

Status Verified

December 1, 2019

Enrollment Period

8 months

First QC Date

December 10, 2019

Last Update Submit

May 10, 2021

Conditions

Keywords

Chronic Fatigue SyndromeMyalgic EncephalomyelitisME/CFSPhysical activityActivity armband

Outcome Measures

Primary Outcomes (1)

  • Feasibility of activity monitoring armband to assess physical activity in ME/CFS patients

    Feasibility of activity monitoring armbands to assess level of physical activity in ME/CFS patients, with comparison of activity data to self-reported questionnaires for quality of life (SF-36 ver.2) and for ME/CFS symptoms (DSQ-SF)

    6 months

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Approximately 30 patients with ME/CFS according to Canadian Consensus Criteria (2003) with disease duration at least 2 years, of age 18-65 years

You may qualify if:

  • Patients wit ME/CFS according to Canadian Consensus Criteria (2003)
  • ME/CFS disease duration at least 2 years
  • Mild, Mild/moderate, Moderate, Moderate/Severe and Severe ME/CFS may be included
  • Signed informed consent

You may not qualify if:

  • Patients with fatigue, who do not meet the diagnostic "Canadian" criteria (2003) for ME/CFS
  • ME/CFS disease duration \< 24 months
  • Patients where the diagnostic workup uncovers other pathology as possible cause of symptoms
  • Serious endogenous depression
  • Lack of ability to complete the study including follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Haukeland University Hospital

Bergen, N-5020, Norway

Location

Related Publications (1)

  • Rekeland IG, Sorland K, Bruland O, Risa K, Alme K, Dahl O, Tronstad KJ, Mella O, Fluge O. Activity monitoring and patient-reported outcome measures in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients. PLoS One. 2022 Sep 19;17(9):e0274472. doi: 10.1371/journal.pone.0274472. eCollection 2022.

Biospecimen

Retention: SAMPLES WITH DNA

Blood samples (serum, plasma, full blood) will be collected at baseline

MeSH Terms

Conditions

Fatigue Syndrome, ChronicMotor Activity

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesEncephalomyelitisNeuroinflammatory DiseasesNervous System DiseasesNeuromuscular DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBehavior

Study Officials

  • Olav Mella, MD, Prof

    Haukeland University Hospital

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 10, 2019

First Posted

December 12, 2019

Study Start

March 11, 2020

Primary Completion

November 20, 2020

Study Completion

November 20, 2020

Last Updated

May 11, 2021

Record last verified: 2019-12

Locations