The Impact of Early Versus Delayed Umbilical Cord Clamping in Preeclamptic Pregnant Patients During Cesarean Section
The Maternal and Neonatal Impact of Early Versus Delayed Umbilical Cord Clamping Among Pregnant Severe Preeclampsia Patients Delivered by Cesarean Section
1 other identifier
interventional
62
1 country
1
Brief Summary
To compare the different maternal and neonatal impacts of early versus delayed umbilical cord clamping among pregnant preeclamptic patients delivered by cesarean section
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 8, 2019
CompletedFirst Posted
Study publicly available on registry
December 10, 2019
CompletedStudy Start
First participant enrolled
January 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2021
CompletedFebruary 23, 2022
February 1, 2022
1.4 years
December 8, 2019
February 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
the intra operative maternal blood loss
To compare the early versus of delayed cord clamping on intra operative blood loss in pregnant patients diagnosed with severe preeclampsia
24 hours
Secondary Outcomes (2)
the neonatal outcome
4 days
The incidence of post partum hemorrhage
24 hours
Study Arms (2)
Early cord clamping
ACTIVE COMPARATORThe umbilical cord will be clamped within 15 seconds from delivery of the baby
Delayed cord clamping
ACTIVE COMPARATORThe umbilical cord will be clamped after 60 seconds from delivery of the baby
Interventions
Comparing and monitoring the maternal blood loss and neonatal effect of delayed umbilical cord clamping and early umbilical cord clamping after delivery of the baby durin cesarean delivery in severe preeclampsia
Eligibility Criteria
You may qualify if:
- Pregnant women candidate for LSCS.
- Age: 20-40 years old.
- Maternal severe preeclampsia
- CS under spinal anesthesia.
- Singleton pregnancy
You may not qualify if:
- Fetal death (IUFD).
- Intrapartum surgical complications ( uterine artery injury or lower segment extension)
- Medical disorders such as Diabetes mellitus or severe anemia
- The need for immediate resuscitation like meconium aspiration .
- Abnormal placentation or placental abruption
- Liquor abnormalities ; oligo hydramnios
- Anomalous fetus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Faculty of Medicine - Cairo University
Cairo, Egypt
Related Publications (1)
Rashwan A, Eldaly A, El-Harty A, Elsherbini M, Abdel-Rasheed M, Eid MM. Delayed versus early umbilical cord clamping for near-term infants born to preeclamptic mothers; a randomized controlled trial. BMC Pregnancy Childbirth. 2022 Jun 25;22(1):515. doi: 10.1186/s12884-022-04831-8.
PMID: 35752762DERIVED
Related Links
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant professor
Study Record Dates
First Submitted
December 8, 2019
First Posted
December 10, 2019
Study Start
January 1, 2020
Primary Completion
May 31, 2021
Study Completion
May 31, 2021
Last Updated
February 23, 2022
Record last verified: 2022-02
Data Sharing
- IPD Sharing
- Will not share