NCT04188704

Brief Summary

The anatomic ACL reconstruction aims at functional restoration of the ACL to its native dimensions, collagen orientation and insertion sites. Even if the anatomic foot prints are correctly chosen for the tibial and femoral tunnels does the position of interference screw in the tibial tunnel alter the ACL orientation? The study hypothesized that the position of interference screw in the tibial tunnel would alter the graft orientation in anatomic ACL reconstruction. The purpose of this study was to compare graft orientation and inclination angle with posterolateral and anteromedial interference screw position in tibial tunnel in aperture fixation techniques.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
108

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2013

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
5.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

November 30, 2019

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 6, 2019

Completed
Last Updated

December 6, 2019

Status Verified

December 1, 2019

Enrollment Period

5.9 years

First QC Date

November 30, 2019

Last Update Submit

December 4, 2019

Conditions

Keywords

ACLscrew fixationgraft inclinationreconstruction

Outcome Measures

Primary Outcomes (1)

  • Inclination angle

    Mean anterior cruciate ligament inclination angle in sagital x-ray (degree)

    6 months

Secondary Outcomes (1)

  • post-operative complications

    6 months

Study Arms (2)

Anterior cruciate ligament normal

PLACEBO COMPARATOR

normal Anterior cruciate ligament reconstruction

Procedure: Interference screw

Anterior cruciate ligament reconstruction

EXPERIMENTAL

Anterior cruciate ligament reconstruction and Position screw fixation

Procedure: Interference screw

Interventions

Anterior cruciate ligament reconstruction (anterior screw fixation or posterior screw fixation)

Anterior cruciate ligament normalAnterior cruciate ligament reconstruction

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • magnetic resonance imaging (MRI) of patients with ACL reconstruction was compared to MRI in which ACL was intact.
  • patients with isolated ACL injury who underwent ACL reconstruction surgery using quadripled hamstrings graft and operated by a single senior surgeon
  • Both pre-operative and post-operative MRI should be available for assessment
  • No history of trauma in the post-operative or rehabilitation period

You may not qualify if:

  • Concomitant bony or other ligament injury to the same knee
  • history of previous surgery to the same knee
  • Revision ACL reconstruction surgery
  • surgery done at other center or by other doctors at our institute
  • Pre-operative and/or post-operative MRI not available

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee InjuriesLeg InjuriesWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator

Study Record Dates

First Submitted

November 30, 2019

First Posted

December 6, 2019

Study Start

January 1, 2013

Primary Completion

December 1, 2018

Study Completion

December 1, 2019

Last Updated

December 6, 2019

Record last verified: 2019-12

Data Sharing

IPD Sharing
Will not share