Effects of Closed and Open Kinetic Chain Exercises

NCT04186143 | Completed

• 1 other identifier: 2019900
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoarthritis (OA) is a heterogeneous pathology characterized by focal cartilage degeneration and the formation of new bone around the subchondral bone and joint, which is the disruption of balance between the processes of destruction and repair in subchondral area. Knee OA is a considerable cause of disability and is present in 2-3% of all disability causes. Exercises are more noticeable than other methods because they are an easy method, low cost and long-lasting. To the best of our knowledge, the studies based on this topic are scarce. Therefore, the aim of this study was to compare the effects of open and closed kinetic chain exercises on pain, functional level, quality of life and muscle strength in patients with knee osteoarthritis.

Conditions

Osteo Arthritis Knee

Outcome Measures

Primary Outcomes (1)

• Visual analogue scale (Pain)

  The Visual Analogue Scale (VAS) consists of a straight line with the endpoints defining extreme limits such as 'no pain at all' and 'pain as bad as it could be'. The patient is asked to mark his pain level on the line between the two endpoints. The distance between 'no pain at all' and the mark then defines the subject's pain. The 11-point numeric scale ranges from '0' representing no pain to '10' representing pain as bad as you can imagine or worst pain imaginable.

  12 weeks

Secondary Outcomes (5)

• The WOMAC Index (Functional Level)

  12 weeks

• Biodex System Pro 4 Isokinetic Strength Dynamometer (Muscle Strength)

  12 weeks

• Biodex System Pro 4 Isokinetic Strength Dynamometer (Muscle Strength)

  12 weeks

• Biodex System Pro 4 Isokinetic Strength Dynamometer (Muscle Strength)

  12 weeks

• 36-Item Short Form Survey (SF-36) (Quality of Life)

  12 weeks

Study Arms (3)

Experimental-Study Group

EXPERIMENTAL

In addition to the conservative treatment of the control group, closed cinetic chain exercises were applied for 12 weeks.

Other: Closed Cinetic Chain Exercises

Active Comparator

ACTIVE COMPARATOR

In addition to the conservative treatment of the control group, opened cinetic chain exercises were applied for 12 weeks.

Other: Open Kinetic Chain Exercises

Control Group

OTHER

Conservative treatment was applied for 12 weeks.

Other: Control Group

Interventions

Closed Cinetic Chain Exercises OTHER

Sit to stand, mini squat, anterior lunge, step up exercises are performed as Closed Cinetic Chain Exercises.

Experimental-Study Group

Open Kinetic Chain Exercises OTHER

Isometric quadriceps, isotonic quadriceps, hip extension and hip adduction exercises are performed as Open Kinetic Chain Exercises.

Active Comparator

Control Group OTHER

Control Group was followed up by conservative treatment and home program for 12 weeks and they were asked to apply the home program three days in a week. Exercise brochure was handed out for home program. Quadriceps strength and harmstring stretch exercises were applied.

Control Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• the presence of knee osteoarthritis Grade 2 and Grade 3 based on Kellgren Lawrence Classification,
• volunteering to participate in the study.

You may not qualify if:

• the presence of active synovitis,
• participation physiotherapy program in the last 6 months,
• systemic and cardiovascular diseases,
• neurological and orthopedic problems affecting walking and standing,
• lower extremity surgery

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Caner KARARTI

Kırşehir, 40100, Turkey (Türkiye)

Location

Related Publications (3)

• Heywood S, McClelland J, Geigle P, Rahmann A, Villalta E, Mentiplay B, Clark R. Force during functional exercises on land and in water in older adults with and without knee osteoarthritis: Implications for rehabilitation. Knee. 2019 Jan;26(1):61-72. doi: 10.1016/j.knee.2018.11.003. Epub 2019 Jan 2.

  PMID: 30611642 RESULT

• Olagbegi OM, Adegoke BO, Odole AC. Effectiveness of three modes of kinetic-chain exercises on quadriceps muscle strength and thigh girth among individuals with knee osteoarthritis. Arch Physiother. 2017 Jul 19;7:9. doi: 10.1186/s40945-017-0036-6. eCollection 2017.

  PMID: 29340203 RESULT

• Resende RA, Kirkwood RN, Deluzio KJ, Morton AM, Fonseca ST. Mild leg length discrepancy affects lower limbs, pelvis and trunk biomechanics of individuals with knee osteoarthritis during gait. Clin Biomech (Bristol). 2016 Oct;38:1-7. doi: 10.1016/j.clinbiomech.2016.08.001. Epub 2016 Aug 3.

  PMID: 27509479 RESULT

MeSH Terms

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: CARE PROVIDER
• Masking Details: Single blinded
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Randomized

Study Record Dates

• First Submitted: November 30, 2019
• First Posted: December 4, 2019
• Study Start: November 20, 2017
• Primary Completion: June 20, 2018
• Study Completion: July 20, 2018
• Last Updated: June 29, 2020

Record last verified: 2020-06

Locations

TU (1)