Effects of Prior Induced Termination of Pregnancy on Complications and Pregnancy Outcomes.
1 other identifier
observational
20,000
1 country
12
Brief Summary
A prospective multicenter cohort study to evaluate effects of prior induced termination of pregnancy on complications and pregnancy outcomes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2019
Longer than P75 for all trials
12 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2019
CompletedFirst Submitted
Initial submission to the registry
November 28, 2019
CompletedFirst Posted
Study publicly available on registry
December 3, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2028
September 12, 2025
September 1, 2025
8.5 years
November 28, 2019
September 5, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
adverse pregnancy outcomes
the rate of different adverse pregnancy outcomes
2028.6
Secondary Outcomes (1)
Complications
2020.6
Interventions
Medically, induced termination of pregnancy (I-TOP) is defined as an intervention to voluntarily terminate a pregnancy (ie, induced abortion) by either surgical or medical means so it does not result in a live birth.
Eligibility Criteria
women who have induced abortion in early pregnancy (\<12 weeks of gestation)
You may qualify if:
- women have induced abortion in early pregnancy (\<12 weeks of gestation).
- permanent population and no tendency to move.
- normal language expression and understanding ability, able to understand research content.
- be able and willing to provide written informed consent and effective contact information, and be willing to cooperate with follow-up investigations.
You may not qualify if:
- above the age of 40
- with history of adverse pregnancy and childbirth
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (12)
Zhongshan Boai Hospital
Zhongshan, Guangdong, China
Zhangjiakou Maternal and Child Health Hospital
Zhangjiakou, Hebei, China
Daqing People's Hospital
Daqing, Heilongjiang, 150000-160000, China
Changzhou Maternal and Child Health Hospital
Changzhou, Jiangsu, China
Yangzhou Maternal and Child Health Hospital
Yangzhou, Jiangsu, China
People's Hospital of Inner Mongolia Autonomous Region
Hohhot, Mongolia Autonomous, China
Qingdao Maternal and Child Health Hospital
Qingdao, Shandong, China
Zaozhuang Maternal and Child Health Hospital
Zaozhuang, Shandong, China
Taiyuan Maternal and Child Health Hospital
Taiyuan, Shanxi, China
Tanggu Maternal and Child Health Hospital
Tanggu, Tianjin Municipality, China
Chongqing Health Center for Women and Children
Chongqing, China
Shenzhen Luohu Maternity and Child Healthcare Hospital
Shenzhen, China
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pei Kaiyan
National Research Institute for Family Planning (NRIFP)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 28, 2019
First Posted
December 3, 2019
Study Start
June 1, 2019
Primary Completion (Estimated)
December 1, 2027
Study Completion (Estimated)
June 1, 2028
Last Updated
September 12, 2025
Record last verified: 2025-09