NCT04183270

Brief Summary

In this study researchers want to learn more about the patient's and treating doctor's concerns about possible bleedings during treatment with drugs preventing blood clots in blood vessels and the heart - so called blood thinner. The study also wants to find out more about the patient's knowledge on the importance, risks and benefits of treatment with this drug group. Patients with irregular heartbeat not caused by valvular heart disease who will start treatment with a blood thinner will be asked by their treating cardiologist to complete a questionnaire related to their knowledge and fear of possible bleedings or stroke (blockage or rupture of a blood vessel to the brain) due to the intake of a blood thinner. The treating doctor will complete a similar questionnaire. The study plans to involve 15 cardiologists and 300 patients in Belgium.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
164

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 21, 2019

Completed
12 days until next milestone

First Posted

Study publicly available on registry

December 3, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

February 10, 2020

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

November 5, 2021

Status Verified

October 1, 2021

Enrollment Period

10 months

First QC Date

November 21, 2019

Last Update Submit

October 28, 2021

Conditions

Outcome Measures

Primary Outcomes (10)

  • Age categories of patients

    Collected via the questionnaire.

    1 day

  • Gender (Female or male) of patients

    Collected via the questionnaire.

    1 day

  • Patients' level of agreement with various statements of using NOACs in general

    By using a 5-point Likert scale (completely disagree, more likely to disagree, no opinion, more likely to agree, completely agree)

    1 day

  • Level of patients fear of having a bleeding on a scale from 0 - 10

    1 day

  • Level of patients fear of having a stroke or thrombosis on a scale from 0 - 10

    1 day

  • Age categories of physicians

    Collected via the questionnaire.

    1 day

  • Gender (Female or male) of physicians

    Collected via the questionnaire.

    1 day

  • Physicans' level of agreement with various statement of using NOACs in general

    By using a 5-point Likert scale (completely disagree, more likely to disagree, no opinion, more likely to agree, completely agree)

    1 day

  • Level of patients fear of having a bleeding assessed by physicans on a scale from 0 - 10

    1 day

  • Level of patients fear of having a stroke or thrombosis assessed by physicians on a scale from 0 - 10

    1 day

Study Arms (2)

Patients

Non-valvular atrial fibrillation (NVAF) patients who will start treatment with a non-VKA oral anticoagulants (NOAC).

Other: Questionnaires

Physicians

Treating physicians for NVAF patients.

Other: Questionnaires

Interventions

The survey will focus on non-valvular atrial fibrillation patients, who will start treatment with a NOAC, and their treating physician.

PatientsPhysicians

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The source population of this study would be approximately 15 cardiologists (hospital or office-based) and 300 NOAC treatment-naïve patients diagnosed with NVAF who will start treatment with a NOAC for this indication.

You may qualify if:

  • Male or female adult patients diagnosed with NVAF.
  • NOAC treatment-naive patients who will start a NOAC treatment.

You may not qualify if:

  • Previous stroke or thrombosis
  • Previous severe bleeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Many locations

Multiple Locations, Belgium

Location

Related Links

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 21, 2019

First Posted

December 3, 2019

Study Start

February 10, 2020

Primary Completion

November 30, 2020

Study Completion

December 31, 2020

Last Updated

November 5, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Availability of this study's data will later be determined according to Bayer's commitment to the EFPIA/PhRMA "Principles for responsible clinical trial data sharing". This pertains to scope, timepoint and process of data access. As such, Bayer commits to sharing upon request from qualified researchers patient-level clinical trial data, study-level clinical trial data, and protocols from clinical trials in patients for medicines and indications approved in the US and EU as necessary for conducting legitimate research. This applies to data on new medicines and indications that have been approved by the EU and US regulatory agencies on or after January 01, 2014. Interested researchers can use www.clinicalstudydatarequest.com to request access to anonymized patient-level data and supporting documents from clinical studies to conduct research. Information on the Bayer criteria for listing studies and other relevant information is provided in the Study sponsors section of the portal.

Locations