An Electronic Intervention to Reduce Cannabis Among Young Adults in Psychiatric Care

NCT04174963 | Terminated

• 1 other identifier: 1445964
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

Cannabis use disorders are common among young adults in psychiatric treatment. Unfortunately, cannabis use can result in deleterious consequences for those in treatment, including developing more severe psychopathology and poorer treatment outcomes. Brief, electronic interventions for cannabis use have been developed for young adults. An example of a frequently used brief electronic intervention for cannabis users is e-Toke. e-Toke can be completed on a computer, tablet or phone, and has been shown to improve motivation to engage in substance use treatment among college students. However, e-Toke is less useful in decreasing the actual frequency of cannabis use. Additionally, e-toke is not tailored to young adults in psychiatric treatment. In this study, the investigators will develop and test a text messaging intervention that can be easily added to the popular computerized intervention e-Toke. The research staff hope the intervention will improve motivation to decrease cannabis use, and decrease the frequency of cannabis use, among young adults in psychiatric outpatient treatment. The text messages will be developed by, and tailored to, young adults in psychiatric treatment and texts will address motivations and barriers to reducing cannabis use in the context of psychiatric disorders. If the text message intervention is found to be an effective addition to e-Toke, this approach can be tested in a larger study, and then disseminated to other young adults in psychiatric treatment.

Conditions

Cannabis Use; Psychiatric Disorder

Outcome Measures

Primary Outcomes (4)

• Change in Self-reported Frequency of Cannabis Use

  This self-report will be obtained using an abbreviated version of the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) nine times throughout the duration of the study. The abbreviated ASSIST will be administered at weeks 2, 4, 5, 6, 7, 8, 9, 10, and 11 of the study.

  Assessed at weeks 2, 4, 5, 6, 7, 8, 9, 10, and 11

• Change in Self-reported Motivation to Reduce Cannabis Use (SOCRATES)

  Motivation to change substance use will be assessed using the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) adapted for cannabis use (19-item questionnaires that assess recognition, ambivalence, and taking steps). Change will be assessed from baseline to 12-weeks follow-up.

  Assessed at baseline and 12 weeks

• Change in Self-reported Motivation to Reduce Cannabis Use (Readiness Ruler)

  Motivation to change substance use will be assessed using the Readiness Ruler (rates degree of readiness to cut down ranging from 1 to 10 for twelve different substance categories). Change will be assessed from baseline to 12-weeks follow-up.

  Assessed at baseline and 12 weeks

• Change in Self-reported Motivation to Reduce Cannabis Use (DBI)

  Motivation to change substance use will be assessed using the Decisional Balance Inventory (16-item measure of the pros and cons of substance use). Change will be assessed from baseline to 12-weeks follow-up.

  Assessed at baseline and 12 weeks

Secondary Outcomes (2)

• Change in Self-reported Psychiatric Symptoms

  Assessed at baseline and 12 weeks

• Change in Self-reported Self-efficacy to Reduce Cannabis Use (SCQ-8)

  Assessed at baseline and 12 weeks

Study Arms (1)

eToke + TPsy

EXPERIMENTAL

All participants will receive the intervention (eToke+TPsy). The intervention consists of eToke (a brief computerized intervention that uses motivational enhancement therapy to improve readiness to decrease cannabis use and increase motivation to engage in substance use treatment) AND 6-8 interactive text messages regarding cannabis use reduction over 4 weeks . Text messages will contain written content, and queries, as well as links to publicly available websites and YouTube videos.

Behavioral: eToke + TPsy

Interventions

eToke + TPsy BEHAVIORAL

Combination of brief computerized intervention (eToke) with Information-Motivation-Behavior based text messages tailored to young adults in psychiatric treatment

eToke + TPsy

Eligibility Criteria

• Age: 18 Years - 28 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• years of age
• Report using cannabis 2 or more times per week
• English speaking
• Have a telephone that can receive text-messages
• Receive psychiatric treatment in the Young Adult Behavioral Health Program or Partial Program at Rhode Island Hospital.
• Be at high risk for psychosis according to mental health guidelines

You may not qualify if:

• Psychiatric symptoms severe enough to preclude meaningful consent or participation, as determined by the treatment psychiatrist and research team
• Current clinical diagnosis of mental retardation or pervasive developmental disorder

Sponsors & Collaborators

• Rhode Island Hospital: lead

Study Sites (1)

Rhode Island Hospital

Providence, Rhode Island, 02903, United States

Location

Related Publications (6)

• Elliott JC, Carey KB. Correcting exaggerated marijuana use norms among college abstainers: a preliminary test of a preventive intervention. J Stud Alcohol Drugs. 2012 Nov;73(6):976-80. doi: 10.15288/jsad.2012.73.976.

  PMID: 23036216 BACKGROUND

• Miller WR, Tonigan JS. Assessing drinkers' motivation for change: The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES). Psychology of Addictive Behaviors 10(20): 81-89, 1996.

  BACKGROUND

• Migneault JP, Pallonen UE, Velicer WF. Decisional balance and stage of change for adolescent drinking. Addict Behav. 1997 May-Jun;22(3):339-51. doi: 10.1016/s0306-4603(96)00252-3.

  PMID: 9183504 BACKGROUND

• Derogatis LR, Melisaratos N. The Brief Symptom Inventory: an introductory report. Psychol Med. 1983 Aug;13(3):595-605.

  PMID: 6622612 BACKGROUND

• Kirisci L, Moss HB, Tarter RE. Psychometric evaluation of the Situational Confidence Questionnaire in adolescents: fitting a graded item response model. Addict Behav. 1996 May-Jun;21(3):303-17. doi: 10.1016/0306-4603(95)00060-7.

  PMID: 8883482 BACKGROUND

• WHO ASSIST Working Group. The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST): development, reliability and feasibility. Addiction. 2002 Sep;97(9):1183-94. doi: 10.1046/j.1360-0443.2002.00185.x.

  PMID: 12199834 BACKGROUND

MeSH Terms

Conditions

Mental Disorders

Study Officials

• Laura Whiteley, MD

  Rhode Island Hospital

  PRINCIPAL INVESTIGATOR

• Larry Brown, MD

  Rhode Island Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 4, 2019
• First Posted: November 22, 2019
• Study Start: November 1, 2019
• Primary Completion: May 24, 2022
• Study Completion: May 24, 2022
• Last Updated: November 18, 2023

Record last verified: 2023-11

Locations

US (1)