NCT04170764

Brief Summary

The purpose of this study is to evaluate how many patients have hemoglobin less than 10 g/dL at post-operative day 1

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
664

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 18, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 20, 2019

Completed
2 days until next milestone

Study Start

First participant enrolled

November 22, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 19, 2020

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 28, 2020

Completed
3.3 years until next milestone

Results Posted

Study results publicly available

September 1, 2023

Completed
Last Updated

September 1, 2023

Status Verified

October 1, 2022

Enrollment Period

6 months

First QC Date

November 18, 2019

Results QC Date

October 19, 2022

Last Update Submit

October 19, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Subjects With POD1 Hemoglobin Less Than 10 g/dL

    Postop Day 1

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients who underwent a total vaginal hysterectomy with concurrent vaginal native tissue prolapse repairs performed by one of four fellowship trained urogynecologists at TriHealth between 10/1/2014 and 10/1/2019. The patients will be identified by CPT codes in the EPIC electronic medical record.

You may qualify if:

  • Total vaginal hysterectomy with or without bilateral salpingectomy/oophorectomy (CPT 58260, 58262, 58263, 58270, 58290, 58291, 58292, 58294)
  • At least one of the following vaginal native tissue prolapse repairs
  • Apical repair with uterosacral ligament suspension (CPT 57283)
  • Apical repair with sacrospinous ligament fixation (CPT 57282)
  • Anterior repair (CPT 57240, 57260, 57284, 57285, 57250)
  • Posterior repair (CPT 45560, 56800, 56810, 57200, 57210, 57250)
  • Surgery by one of four fellowship trained urogynecologists at TriHealth

You may not qualify if:

  • Concomitant surgical procedure by a second surgeon
  • Malignancy identified at the time of surgery or active malignancy
  • Cases converted to open hysterectomy or prolapse repairs
  • Prolapse repair completed robotically
  • Prolapse repair completed with mesh
  • Known coagulopathy
  • Patient on long term preoperative anticoagulant medication (Arixtra, Coumadin, Eliquis, Heparin, Lovenox, Pradaxa, Savaysa, Xarelto)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cincinnati Urogynecology Associates

Cincinnati, Ohio, 45220, United States

Location

Related Publications (1)

  • Aldrich ER, Pauls RN. Clinical Benefit of Routine Postoperative Hemoglobin Testing After Vaginal Hysterectomy and Reconstruction for Symptomatic Pelvic Organ Prolapse. Female Pelvic Med Reconstr Surg. 2022 Jan 1;28(1):40-44. doi: 10.1097/SPV.0000000000001056.

Results Point of Contact

Title
Dr. Emily Aldrich
Organization
TriHealth

Study Officials

  • Rachel Pauls, MD

    TriHealth - Cincinnati Urogynecology Associates

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 18, 2019

First Posted

November 20, 2019

Study Start

November 22, 2019

Primary Completion

May 19, 2020

Study Completion

May 28, 2020

Last Updated

September 1, 2023

Results First Posted

September 1, 2023

Record last verified: 2022-10

Locations