NCT04163770

Brief Summary

Pacemakers were introduced into clinical practice several decades ago and currently are used in a growing number of patients. Since insertion of the first cardiac Pacemaker in 1958, vast changes have occurred in both the technology of the devices and their indications. Devices have evolved from single-lead and fixed-rate systems to multi chamber rate-responsive systems with increasingly sophisticated software . Pediatric Pacemaker implants comprise less than 1 % of all implants. The indications for pacing in newborns and infants are divided predominantly into three groups: congenital abnormalities of the conduction system, acquired heart blocks after cardiac surgery for correction of congenital defects, and sinus node diseases

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 28, 2019

Completed
18 days until next milestone

First Posted

Study publicly available on registry

November 15, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

January 15, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2021

Completed
Last Updated

November 15, 2019

Status Verified

November 1, 2019

Enrollment Period

1 year

First QC Date

October 28, 2019

Last Update Submit

November 14, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Performance of pacemakers in children

    the performance will be assessed by Ventricular impedence in ohms

    1 year

  • Performance of pacemakers in children

    the performance will be assessed by ventricular capture threshold in volt

    1 year

Study Arms (2)

performance of pacemaker at time of implantation

EXPERIMENTAL
Device: caliberation of pacemaker

performance of pacemaker 6 months after implantation

EXPERIMENTAL
Device: caliberation of pacemaker

Interventions

evaluation of ventricular impedence, ventricular sensing, ventricular capture threshold

performance of pacemaker at time of implantation

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Pediatric age group 0 month -18 years Indicated for permanent cardiac pacing

You may not qualify if:

  • Cardiomyopathy unrelated to rhythm disturbance.
  • Significant systemic disease apart from the cardiac one

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Garnreiter J, Whitaker P, Pilcher T, Etheridge S, Saarel E. Lumenless pacing leads: performance and extraction in pediatrics and congenital heart disease. Pacing Clin Electrophysiol. 2015 Jan;38(1):42-7. doi: 10.1111/pace.12508. Epub 2014 Sep 16.

    PMID: 25224253BACKGROUND

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant lecturer of pediatric

Study Record Dates

First Submitted

October 28, 2019

First Posted

November 15, 2019

Study Start

January 15, 2020

Primary Completion

January 15, 2021

Study Completion

February 15, 2021

Last Updated

November 15, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing
Will not share