NCT04162405

Brief Summary

The aim of this study is to evaluate hearing characteristics in patients with and without tinnitus using DPOAE and specific tinnitus severity index (TSI) and tinnitus handicap inventory (THI) questionnaires in both groups. Purpose of the research: Demonstrate that the characteristics of tinnitus depend on the presence and magnitude of hearing loss. Research participants: 150 patients coming for further audiological treatment due to tinnitus. Data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be performed.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2019

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

November 11, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 14, 2019

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2020

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2020

Completed
Last Updated

November 20, 2019

Status Verified

November 1, 2019

Enrollment Period

8 months

First QC Date

November 11, 2019

Last Update Submit

November 18, 2019

Conditions

Keywords

tinnitussensorineural hearing lossotoacoustic emissionnormacusisquestionnaire

Outcome Measures

Primary Outcomes (1)

  • Establishing correlations between DPOAE, TA, and THI values

    Evaluating whethere there are certain characteristics of tinnitus correlated with patients with and without hearing loss

    2 hours

Study Arms (2)

Patients with tinnitus and hearing loss

Patients with tinnitus and average speech-frequency tonal audiogram threshold \>30 dB

Behavioral: Tinnitus Handicap Inventory Test

Patients with tinnitus without hearing loss

Patients with tinnitus and average speech-frequency tonal audiogram threshold \<30 dB

Behavioral: Tinnitus Handicap Inventory Test

Interventions

A prospective cohort nonrandomized study of non-masked parallel paired groups. The data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be performed.

Also known as: Distortion Product Otoacoustic Emission
Patients with tinnitus and hearing lossPatients with tinnitus without hearing loss

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with and without hearing loss suffering from tinnitus, scheduled for diagnostic in a tertiary audiological center.

You may qualify if:

  • adulthood (\> 18 years), tinnitus as the primary reason for referring to diagnostic processing, and consent to complete two on-site tinnitus questionnaires

You may not qualify if:

  • conductive hearing loss and incomplete questionnaires

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Center Sestre milosrdnice

Zagreb, 10000, Croatia

RECRUITING

MeSH Terms

Conditions

TinnitusHearing LossOtorhinolaryngologic DiseasesHearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Robert Trotić, MD, PhD

    Department of Otorhinolaryngology and Head and Neck Surgery

    STUDY CHAIR

Central Study Contacts

Andro Košec, MD, PhD

CONTACT

Mihael Ries, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Consultant Otorhinolaryngologist and Head and Neck Surgeon

Study Record Dates

First Submitted

November 11, 2019

First Posted

November 14, 2019

Study Start

November 1, 2019

Primary Completion

June 30, 2020

Study Completion

July 1, 2020

Last Updated

November 20, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing
Will not share

Locations