A Psychosocial Intervention for Patients With Colorectal Cancer and Their Family Caregivers

NCT04159363 | Unknown DMC

• 1 other identifier: SCS2018
• Study Type: interventional
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to develop a smartphone-based psychosocial intervention for patients with colorectal cancer and their family caregivers and to improve patients' confidence in self-care, psychological well-being, social support, quality of life, and satisfaction with care, as well as caregivers' burden, psychological well-being, and quality of life. The study also aims to explore patients' and their caregivers' perceptions of the intervention and routine care. A multi-centre two-arm experimental study design is used in this study. A total of 100 patient-caregiver dyads will be recruited and randomly allocated to either the control group (receiving routine care alone) or the intervention group (receiving routine care plus the psychosocial intervention). After completed the study, 15 patient-caregiver dyads will be invited for interviews to explore their perceptions on the intervention and/or routine care. This study will generate evidence on the effectiveness of the easily accessible and sustainable smartphone-based psychosocial intervention.

Conditions

Colorectal Cancer

Keywords

psychosocial intervention; smartphone-based; patient; colorectal cancer; caregiver; randomised controlled trial

Outcome Measures

Primary Outcomes (2)

• Colorectal cancer patients' self-efficacy

  The level of patient's self-efficacy will be measured by the 10-item General Self-Efficacy Scale (GSE). The General Self-Efficacy (GSE) Scale is a 4-point Likert scale (1 = not at all true, 2 = hardly true, 3 = moderately true, 4 = exactly true). The sum score ranges between 10 and 40 with a higher score indicating more self-efficacy.

  Patients' self-efficacy will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

• Caregivers' quality of life

  Caregivers' quality of life will be measured by 35-item Caregiver Quality of Life Index Cancer (CQOLC). Each item is scored from 0 (not at all) to 4 (very much). The total possible score is 140, with higher scores representing better quality of life.

  Caregivers' quality of life will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

Secondary Outcomes (6)

• Patients' anxiety and depression

  will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

• Patients' Social support

  Patients' social support will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

• Patients' Health-related quality of life

  Patients' health-related quality of life will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

• Patients' Satisfaction with care

  Patients' satisfaction with care will be assessed at baseline (around 2 weeks before surgery) ,and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

• Caregivers' burden

  Caregivers' burden will be assessed at baseline (around 2 weeks before surgery) and assessing changes between baseline and around 2 weeks after the surgery and 3 months after the surgery.

Study Arms (2)

Intervention group

EXPERIMENTAL

Participants in the intervention group will receive an interactive Colorectal Cancer self-Management enhancement smartphone-based psychosocial intervention programme (iCanManage) in addition to routine care provided by the respective hospitals.

Other: An interactive Colorectal Cancer self-Management enhancement smartphone-based psychosocial intervention programme (iCanManage)

Control group

NO INTERVENTION

Participants in the control group will receive routine care provided by the respective hospitals . The routine care includes normal consultation with their attending physician, information concerning treatment plans, such as surgical procedures and its associated risks, preoperative preparations and postoperative care, treatment after discharge and/or subsequent adjunct therapy if required.

Interventions

An interactive Colorectal Cancer self-Management enhancement smartphone-based psychosocial intervention programme (iCanManage) OTHER

The iCanManage consists of two components: (1a) Existing functions from the BuddyCare mobile application that provide a comprehensive 29 day-by-day perioperative guide for patients who will be undergoing colorectal elective surgery; (1b) a dashboard for healthcare professionals to monitor patients and their caregivers' well-being as well as allow mutual communication; and (2) Newly developed digitalised psychosocial content (e.g., mindfulness-based activities with audio cover, video materials related to positive psychology, patient ambassadors' success stories and relevant psychoeducation) tailored for colorectal cancer patients and caregivers, with the aim of providing them emotional and psychosocial support.

Intervention group

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 21 years old and above;
• Diagnosed with primary colorectal cancer;
• Scheduled for elective colorectal surgeries;
• Able to read and speak English and/or Mandarin;
• Have a smartphone with internet access; and
• Have one identifiable main family caregiver
• Aged 21 years old and above;
• Main family caregiver of the patient
• Able to read and speak English and/or Mandarin; and
• Have a smartphone with internet access

You may not qualify if:

• visual or hearing impairments; and/or
• cognitive impairments/mental disorders identified in their medical record

Sponsors & Collaborators

• Singapore Cancer Society: lead
• National University Hospital, Singapore: collaborator
• Singapore General Hospital: collaborator

Related Publications (74)

• Al Daken LI, Ahmad MM. The implementation of mindfulness-based interventions and educational interventions to support family caregivers of patients with cancer: A systematic review. Perspect Psychiatr Care. 2018 Jul;54(3):441-452. doi: 10.1111/ppc.12286. Epub 2018 May 10.

  PMID: 29745417 BACKGROUND

• Ang SG, Chen HC, Siah RJ, He HG, Klainin-Yobas P. Stressors relating to patient psychological health following stoma surgery: an integrated literature review. Oncol Nurs Forum. 2013 Nov;40(6):587-94. doi: 10.1188/13.ONF.587-594.

  PMID: 24161637 BACKGROUND

• Badr H, Lipnick D, Diefenbach MA, Posner M, Kotz T, Miles B, Genden E. Development and usability testing of a web-based self-management intervention for oral cancer survivors and their family caregivers. Eur J Cancer Care (Engl). 2016 Sep;25(5):806-21. doi: 10.1111/ecc.12396. Epub 2015 Oct 27.

  PMID: 26507369 BACKGROUND

• Badr H, Carmack CL, Diefenbach MA. Psychosocial interventions for patients and caregivers in the age of new communication technologies: opportunities and challenges in cancer care. J Health Commun. 2015;20(3):328-42. doi: 10.1080/10810730.2014.965369. Epub 2015 Jan 28.

  PMID: 25629218 BACKGROUND

• Bandura, A. (1997). Self-efficacy: The Exercise of Control. New York: Freeman.

  BACKGROUND

• Bazaliński, D., Salacinska, I., Wiech, P. & Kozka, M. (2014). Life satisfaction and self-efficacy in patients with stoma. Progress in Health Sciences, 4(2), 22-30.

  BACKGROUND

• Bellg AJ, Borrelli B, Resnick B, Hecht J, Minicucci DS, Ory M, Ogedegbe G, Orwig D, Ernst D, Czajkowski S; Treatment Fidelity Workgroup of the NIH Behavior Change Consortium. Enhancing treatment fidelity in health behavior change studies: best practices and recommendations from the NIH Behavior Change Consortium. Health Psychol. 2004 Sep;23(5):443-51. doi: 10.1037/0278-6133.23.5.443.

  PMID: 15367063 BACKGROUND

• Bevans M, Sternberg EM. Caregiving burden, stress, and health effects among family caregivers of adult cancer patients. JAMA. 2012 Jan 25;307(4):398-403. doi: 10.1001/jama.2012.29.

  PMID: 22274687 BACKGROUND

• Butler DL. Early postoperative complications following ostomy surgery: a review. J Wound Ostomy Continence Nurs. 2009 Sep-Oct;36(5):513-9; quiz 520-1. doi: 10.1097/WON.0b013e3181b35eaa.

  PMID: 19752661 BACKGROUND

• Raingruber B. The effectiveness of psychosocial interventions with cancer patients: an integrative review of the literature (2006-2011). ISRN Nurs. 2011;2011:638218. doi: 10.5402/2011/638218. Epub 2011 Nov 16.

  PMID: 22191052 BACKGROUND

• Bradley EH, Curry LA, Devers KJ. Qualitative data analysis for health services research: developing taxonomy, themes, and theory. Health Serv Res. 2007 Aug;42(4):1758-72. doi: 10.1111/j.1475-6773.2006.00684.x.

  PMID: 17286625 BACKGROUND

• Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77-101.

  BACKGROUND

• Carlson, L., & Speca, M. (2011). Mindfulness-Based Cancer Recovery: A step-by-step MBSR Approach to help you cope with treatment & reclaim your life. Oakland, CA: New Harbinger Publications.

  BACKGROUND

• Carter PA. A brief behavioral sleep intervention for family caregivers of persons with cancer. Cancer Nurs. 2006 Mar-Apr;29(2):95-103. doi: 10.1097/00002820-200603000-00003.

  PMID: 16565618 BACKGROUND

• Chawla N, Butler EN, Lund J, Warren JL, Harlan LC, Yabroff KR. Patterns of colorectal cancer care in Europe, Australia, and New Zealand. J Natl Cancer Inst Monogr. 2013;2013(46):36-61. doi: 10.1093/jncimonographs/lgt009.

  PMID: 23962509 BACKGROUND

• Chenail, R. J. (2011). How to conduct clinical qualitative research on the patient's experience. Qualitative Report, 16(4), 1173-1190.

  BACKGROUND

• Cotrim H, Pereira G. Impact of colorectal cancer on patient and family: implications for care. Eur J Oncol Nurs. 2008 Jul;12(3):217-26. doi: 10.1016/j.ejon.2007.11.005.

  PMID: 18567538 BACKGROUND

• Doig GS, Simpson F. Randomization and allocation concealment: a practical guide for researchers. J Crit Care. 2005 Jun;20(2):187-91; discussion 191-3. doi: 10.1016/j.jcrc.2005.04.005.

  PMID: 16139163 BACKGROUND

• Eaton LH, Doorenbos AZ, Schmitz KL, Carpenter KM, McGregor BA. Establishing treatment fidelity in a web-based behavioral intervention study. Nurs Res. 2011 Nov-Dec;60(6):430-5. doi: 10.1097/NNR.0b013e31823386aa.

  PMID: 22048559 BACKGROUND

• Fish JA, Ettridge K, Sharplin GR, Hancock B, Knott VE. Mindfulness-based cancer stress management: impact of a mindfulness-based programme on psychological distress and quality of life. Eur J Cancer Care (Engl). 2014 May;23(3):413-21. doi: 10.1111/ecc.12136. Epub 2013 Oct 10.

  PMID: 24118428 BACKGROUND

• Fu F, Zhao H, Tong F, Chi I. A Systematic Review of Psychosocial Interventions to Cancer Caregivers. Front Psychol. 2017 May 23;8:834. doi: 10.3389/fpsyg.2017.00834. eCollection 2017.

  PMID: 28596746 BACKGROUND

• Gonzalez-Saenz de Tejada M, Bilbao A, Bare M, Briones E, Sarasqueta C, Quintana JM, Escobar A. Association of social support, functional status, and psychological variables with changes in health-related quality of life outcomes in patients with colorectal cancer. Psychooncology. 2016 Aug;25(8):891-7. doi: 10.1002/pon.4022. Epub 2015 Nov 18.

  PMID: 26582649 BACKGROUND

• Grassi L, Spiegel D, Riba M. Advancing psychosocial care in cancer patients. F1000Res. 2017 Dec 4;6:2083. doi: 10.12688/f1000research.11902.1. eCollection 2017.

  PMID: 29259774 BACKGROUND

• Grimmett C, Haviland J, Winter J, Calman L, Din A, Richardson A, Smith PWF, Foster C. Colorectal cancer patient's self-efficacy for managing illness-related problems in the first 2 years after diagnosis, results from the ColoREctal Well-being (CREW) study. J Cancer Surviv. 2017 Oct;11(5):634-642. doi: 10.1007/s11764-017-0636-x. Epub 2017 Aug 19.

  PMID: 28822053 BACKGROUND

• Gustafson DH, DuBenske LL, Namkoong K, Hawkins R, Chih MY, Atwood AK, Johnson R, Bhattacharya A, Carmack CL, Traynor AM, Campbell TC, Buss MK, Govindan R, Schiller JH, Cleary JF. An eHealth system supporting palliative care for patients with non-small cell lung cancer: a randomized trial. Cancer. 2013 May 1;119(9):1744-51. doi: 10.1002/cncr.27939. Epub 2013 Jan 25.

  PMID: 23355273 BACKGROUND

• Hildebrandt C, Mayer H, Koller A. Experiences of patients with colorectal cancer from diagnosis until completion of treatment: A meta-ethnography approach. Psychooncology. 2019 Feb;28(2):219-227. doi: 10.1002/pon.4946. Epub 2018 Dec 28.

  PMID: 30447170 BACKGROUND

• Huh JW. Stoma Creation After Surgery for Rectal Cancer: Temporary or Permanent? Ann Coloproctol. 2015 Jun;31(3):82. doi: 10.3393/ac.2015.31.3.82. No abstract available.

  PMID: 26161373 BACKGROUND

• House JS, Landis KR, Umberson D. Social relationships and health. Science. 1988 Jul 29;241(4865):540-5. doi: 10.1126/science.3399889.

  PMID: 3399889 BACKGROUND

• Johns SA, Brown LF, Beck-Coon K, Talib TL, Monahan PO, Giesler RB, Tong Y, Wilhelm L, Carpenter JS, Von Ah D, Wagner CD, de Groot M, Schmidt K, Monceski D, Danh M, Alyea JM, Miller KD, Kroenke K. Randomized controlled pilot trial of mindfulness-based stress reduction compared to psychoeducational support for persistently fatigued breast and colorectal cancer survivors. Support Care Cancer. 2016 Oct;24(10):4085-96. doi: 10.1007/s00520-016-3220-4. Epub 2016 May 17.

  PMID: 27189614 BACKGROUND

• Kabat-Zinn, J. (2003), Mindfulness-Based Interventions in Context: Past, Present, and Future. Clinical Psychology: Science and Practice, 10: 144-156. doi:10.1093/clipsy.bpg016

  BACKGROUND

• Kaltenbaugh DJ, Klem ML, Hu L, Turi E, Haines AJ, Hagerty Lingler J. Using Web-based interventions to support caregivers of patients with cancer: a systematic review. Oncol Nurs Forum. 2015 Mar;42(2):156-64. doi: 10.1188/15.ONF.156-164.

  PMID: 25806882 BACKGROUND

• Karimi M, Brazier J. Health, Health-Related Quality of Life, and Quality of Life: What is the Difference? Pharmacoeconomics. 2016 Jul;34(7):645-9. doi: 10.1007/s40273-016-0389-9.

  PMID: 26892973 BACKGROUND

• Kaynar, G. O. & Vural, F. (2018). Assessment of the caregiver burden of caregivers of colorectal cancer patients. Turkish Journal of Colorectal Disease, 28, 164-171. DOI: 10.4274/tjcd.26121

  BACKGROUND

• LeSeure P, Chongkham-Ang S. The Experience of Caregivers Living with Cancer Patients: A Systematic Review and Meta-Synthesis. J Pers Med. 2015 Nov 19;5(4):406-39. doi: 10.3390/jpm5040406.

  PMID: 26610573 BACKGROUND

• Liao, C. & Qin, Y. (2014). Factors associated with stoma quality of life among stoma patients. International Journal of Nursing Sciences, 1(2), 196 - 201. https://doi.org/10.1016/j.ijnss.2014.05.007

  BACKGROUND

• Lim, S. H. (2017). Developing and testing the preliminary effects of stoma psychosocial intervention programme on outcomes of colorectal cancer patients with stoma: a mixed methods study. PhD thesis. Singapore: National University of Singapore.

  BACKGROUND

• Hoon LS, Chi Sally CW, Hong-Gu H. Effect of psychosocial interventions on outcomes of patients with colorectal cancer: a review of the literature. Eur J Oncol Nurs. 2013 Dec;17(6):883-91. doi: 10.1016/j.ejon.2013.05.001. Epub 2013 Jun 4.

  PMID: 23759360 BACKGROUND

• Lim SH, Chan SW, He HG. Patients' Experiences of Performing Self-care of Stomas in the Initial Postoperative Period. Cancer Nurs. 2015 May-Jun;38(3):185-93. doi: 10.1097/NCC.0000000000000158.

  PMID: 24836957 BACKGROUND

• Loi, T. T. C. (2016). Developing and testing the effects of a psychoeducation intervention on patients with colorectal cancer: a mixed method study. PhD thesis, Singapore: National University of Singapore.

  BACKGROUND

• Lu LC, Huang XY, Chen CC. The lived experiences of patients with post-operative rectal cancer who suffer from altered bowel function: A phenomenological study. Eur J Oncol Nurs. 2017 Dec;31:69-76. doi: 10.1016/j.ejon.2017.10.004. Epub 2017 Nov 6.

  PMID: 29173830 BACKGROUND

• Machin, D., Campbell, M., Fayers, P., & Pinol, A. (1997). Sample size tables for clinical studies (2nd ed.). Oxford: Blackwell Science.

  BACKGROUND

• Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010-2020. J Natl Cancer Inst. 2011 Jan 19;103(2):117-28. doi: 10.1093/jnci/djq495. Epub 2011 Jan 12.

  PMID: 21228314 BACKGROUND

• Mehta R, Sharma K, Potters L, Wernicke AG, Parashar B. Evidence for the Role of Mindfulness in Cancer: Benefits and Techniques. Cureus. 2019 May 9;11(5):e4629. doi: 10.7759/cureus.4629.

  PMID: 31312555 BACKGROUND

• Melnyk M, Casey RG, Black P, Koupparis AJ. Enhanced recovery after surgery (ERAS) protocols: Time to change practice? Can Urol Assoc J. 2011 Oct;5(5):342-8. doi: 10.5489/cuaj.11002.

  PMID: 22031616 BACKGROUND

• Mizuno M, Kakuta M, Ono Y, Kato A, Inoue Y. Experiences of Japanese patients with colorectal cancer during the first six months after surgery. Oncol Nurs Forum. 2007 Jul;34(4):869-76. doi: 10.1188/07.ONF.869-876.

  PMID: 17723988 BACKGROUND

• Mosher CE, Adams RN, Helft PR, O'Neil BH, Shahda S, Rattray NA, Champion VL. Family caregiving challenges in advanced colorectal cancer: patient and caregiver perspectives. Support Care Cancer. 2016 May;24(5):2017-2024. doi: 10.1007/s00520-015-2995-z. Epub 2015 Nov 4.

  PMID: 26530227 BACKGROUND

• Ni X, Jia D, Chen Y, Wang L, Suo J. Is the Enhanced Recovery After Surgery (ERAS) Program Effective and Safe in Laparoscopic Colorectal Cancer Surgery? A Meta-Analysis of Randomized Controlled Trials. J Gastrointest Surg. 2019 Jul;23(7):1502-1512. doi: 10.1007/s11605-019-04170-8. Epub 2019 Mar 11.

  PMID: 30859422 BACKGROUND

• Nikoletti S, Young J, Levitt M, King M, Chidlow C, Hollingsworth S. Bowel problems, self-care practices, and information needs of colorectal cancer survivors at 6 to 24 months after sphincter-saving surgery. Cancer Nurs. 2008 Sep-Oct;31(5):389-98. doi: 10.1097/01.NCC.0000305759.04357.1b.

  PMID: 18772664 BACKGROUND

• Northouse L, Kershaw T, Mood D, Schafenacker A. Effects of a family intervention on the quality of life of women with recurrent breast cancer and their family caregivers. Psychooncology. 2005 Jun;14(6):478-91. doi: 10.1002/pon.871.

  PMID: 15599947 BACKGROUND

• Northouse LL, Mood DW, Schafenacker A, Montie JE, Sandler HM, Forman JD, Hussain M, Pienta KJ, Smith DC, Kershaw T. Randomized clinical trial of a family intervention for prostate cancer patients and their spouses. Cancer. 2007 Dec 15;110(12):2809-18. doi: 10.1002/cncr.23114.

  PMID: 17999405 BACKGROUND

• Ohlsson-Nevo E, Andershed B, Nilsson UG, Anderzen-Carlsson A. Finding a wider horizon: experiences of being a next-of-kin of a person suffering from colorectal cancer as told after having participated in a psychoeducational program. Eur J Oncol Nurs. 2013 Jun;17(3):324-30. doi: 10.1016/j.ejon.2012.09.001. Epub 2012 Oct 1.

  PMID: 23036312 BACKGROUND

• Ohlsson-Nevo E, Karlsson J, Nilsson U. Effects of a psycho-educational programme on health-related quality of life in patients treated for colorectal and anal cancer: A feasibility trial. Eur J Oncol Nurs. 2016 Apr;21:181-8. doi: 10.1016/j.ejon.2015.10.002. Epub 2015 Nov 28.

  PMID: 26643400 BACKGROUND

• Palma E, Simonetti V, Franchelli P, Pavone D, Cicolini G. An observational study of family caregivers' quality of life caring for patients with a stoma. Gastroenterol Nurs. 2012 Mar-Apr;35(2):99-104. doi: 10.1097/SGA.0b013e31824c2326.

  PMID: 22472669 BACKGROUND

• Qian H, Yuan C. Factors associated with self-care self-efficacy among gastric and colorectal cancer patients. Cancer Nurs. 2012 May-Jun;35(3):E22-31. doi: 10.1097/NCC.0b013e31822d7537.

  PMID: 22067688 BACKGROUND

• Quinten C, Coens C, Mauer M, Comte S, Sprangers MA, Cleeland C, Osoba D, Bjordal K, Bottomley A; EORTC Clinical Groups. Baseline quality of life as a prognostic indicator of survival: a meta-analysis of individual patient data from EORTC clinical trials. Lancet Oncol. 2009 Sep;10(9):865-71. doi: 10.1016/S1470-2045(09)70200-1. Epub 2009 Aug 18.

  PMID: 19695956 BACKGROUND

• Rehse B, Pukrop R. Effects of psychosocial interventions on quality of life in adult cancer patients: meta analysis of 37 published controlled outcome studies. Patient Educ Couns. 2003 Jun;50(2):179-86. doi: 10.1016/s0738-3991(02)00149-0.

  PMID: 12781933 BACKGROUND

• Sandelowski M. What's in a name? Qualitative description revisited. Res Nurs Health. 2010 Feb;33(1):77-84. doi: 10.1002/nur.20362.

  PMID: 20014004 BACKGROUND

• Schellekens MPJ, van den Hurk DGM, Prins JB, Donders ART, Molema J, Dekhuijzen R, van der Drift MA, Speckens AEM. Mindfulness-based stress reduction added to care as usual for lung cancer patients and/or their partners: A multicentre randomized controlled trial. Psychooncology. 2017 Dec;26(12):2118-2126. doi: 10.1002/pon.4430. Epub 2017 Apr 26.

  PMID: 28337821 BACKGROUND

• Schulz KF, Grimes DA. Allocation concealment in randomised trials: defending against deciphering. Lancet. 2002 Feb 16;359(9306):614-8. doi: 10.1016/S0140-6736(02)07750-4.

  PMID: 11867132 BACKGROUND

• Shahi V, Lapid MI, Kung S, Atherton PJ, Sloan JA, Clark MM, Rummans TA. Do age and quality of life of patients with cancer influence quality of life of the caregiver? J Geriatr Oncol. 2014 Jul;5(3):331-6. doi: 10.1016/j.jgo.2014.03.003. Epub 2014 Apr 14.

  PMID: 24726867 BACKGROUND

• Simmons KL, Smith JA, Bobb KA, Liles LL. Adjustment to colostomy: stoma acceptance, stoma care self-efficacy and interpersonal relationships. J Adv Nurs. 2007 Dec;60(6):627-35. doi: 10.1111/j.1365-2648.2007.04446.x.

  PMID: 18039249 BACKGROUND

• Smith F, Ohlen J, Persson LO, Carlsson E. Daily Assessment of Stressful events and Coping in early post-operative recovery after colorectal cancer surgery. Eur J Cancer Care (Engl). 2018 Mar;27(2):e12829. doi: 10.1111/ecc.12829. Epub 2018 Jan 24.

  PMID: 29363821 BACKGROUND

• Tamagawa R, Garland S, Vaska M, Carlson LE. Who benefits from psychosocial interventions in oncology? A systematic review of psychological moderators of treatment outcome. J Behav Med. 2012 Dec;35(6):658-73. doi: 10.1007/s10865-012-9398-0. Epub 2012 Jan 22.

  PMID: 22271329 BACKGROUND

• Thiele RH, Rea KM, Turrentine FE, Friel CM, Hassinger TE, McMurry TL, Goudreau BJ, Umapathi BA, Kron IL, Sawyer RG, Hedrick TL. Standardization of care: impact of an enhanced recovery protocol on length of stay, complications, and direct costs after colorectal surgery. J Am Coll Surg. 2015 Apr;220(4):430-43. doi: 10.1016/j.jamcollsurg.2014.12.042. Epub 2015 Jan 9.

  PMID: 25797725 BACKGROUND

• Thumboo J, Fong KY, Machin D, Chan SP, Soh CH, Leong KH, Feng PH, Thio St, Boey ML. Quality of life in an urban Asian population: the impact of ethnicity and socio-economic status. Soc Sci Med. 2003 Apr;56(8):1761-72. doi: 10.1016/s0277-9536(02)00171-5.

  PMID: 12639592 BACKGROUND

• Treanor CJ, Santin O, Prue G, Coleman H, Cardwell CR, O'Halloran P, Donnelly M. Psychosocial interventions for informal caregivers of people living with cancer. Cochrane Database Syst Rev. 2019 Jun 17;6(6):CD009912. doi: 10.1002/14651858.CD009912.pub2.

  PMID: 31204791 BACKGROUND

• Waldron EA, Janke EA, Bechtel CF, Ramirez M, Cohen A. A systematic review of psychosocial interventions to improve cancer caregiver quality of life. Psychooncology. 2013 Jun;22(6):1200-7. doi: 10.1002/pon.3118. Epub 2012 Jun 25.

  PMID: 22729992 BACKGROUND

• Wang W, Zheng X, He HG, Thompson DR. Psychometric testing of the Chinese Mandarin version of the Medical Outcomes Study Social Support Survey in patients with coronary heart disease in mainland China. Qual Life Res. 2013 Oct;22(8):1965-71. doi: 10.1007/s11136-012-0345-x. Epub 2013 Jan 19.

  PMID: 23334944 BACKGROUND

• Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA. 1995 Jan 4;273(1):59-65.

  PMID: 7996652 BACKGROUND

• Worster B, Holmes S. A phenomenological study of the postoperative experiences of patients undergoing surgery for colorectal cancer. Eur J Oncol Nurs. 2009 Dec;13(5):315-22. doi: 10.1016/j.ejon.2009.04.008. Epub 2009 May 30.

  PMID: 19482512 BACKGROUND

• Wu HK, Chau JP, Twinn S. Self-efficacy and quality of life among stoma patients in Hong Kong. Cancer Nurs. 2007 May-Jun;30(3):186-93. doi: 10.1097/01.NCC.0000270704.34296.86.

  PMID: 17510581 BACKGROUND

• Yabroff KR, Kim Y. Time costs associated with informal caregiving for cancer survivors. Cancer. 2009 Sep 15;115(18 Suppl):4362-73. doi: 10.1002/cncr.24588.

  PMID: 19731345 BACKGROUND

• Zhuang CL, Ye XZ, Zhang XD, Chen BC, Yu Z. Enhanced recovery after surgery programs versus traditional care for colorectal surgery: a meta-analysis of randomized controlled trials. Dis Colon Rectum. 2013 May;56(5):667-78. doi: 10.1097/DCR.0b013e3182812842.

  PMID: 23575408 BACKGROUND

• Wan SW, Chong CS, Toh EL, Lim SH, Loi CT, Lew YFH, Chua MCH, Jee XP, Liu G, Zhu L, Pikkarainen M, He HG. A Theory-Based, Multidisciplinary Approach to Cocreate a Patient-Centric Digital Solution to Enhance Perioperative Health Outcomes Among Colorectal Cancer Patients and Their Family Caregivers: Development and Evaluation Study. J Med Internet Res. 2021 Dec 7;23(12):e31917. doi: 10.2196/31917.

  PMID: 34878991 DERIVED

Related Links

• Enhanced Recovery after Surgery
• Singapore Cancer Registry. Cancer Incidence and Mortality 2003 - 2012 and Selected Trends 1973-2012 In Singapore
• World Health Organization (WHO). Cancer control: diagnosis and treatment.

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Hong-Gu HE, PhD

  National University of Singapore

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Hong-Gu HE, PhD

CONTACT

+6565167448; nurhhg@nus.edu.sg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: October 15, 2019
• First Posted: November 12, 2019
• Study Start: February 1, 2020
• Primary Completion: January 31, 2021
• Study Completion: January 31, 2021
• Last Updated: November 12, 2019

Record last verified: 2019-11

Data Sharing

• IPD Sharing: Will not share