Using Social Media to Deliver HIV Self-Testing Kits and Link to Online PrEP Services

NCT04155502 | Completed

• 2 other identifiers: CTN-0083, STUDY00031899UG1DA040309
• Study Type: observational
• Target: 272
• Locations: 1 country
• Sites: 1

Brief Summary

The primary objective of this study is to compare the relative effectiveness of three web-based platforms: social media sites (e.g., Facebook), dating applications \[apps\] (e.g., Grindr), and informational sites (e.g., Google) to promote self-testing of Human Immunodeficiency Virus (HIV) infection among men who have sex with men (MSM) who are at increased risk of HIV exposure and/or infection. In addition, we will measure Pre-Exposure Prophylaxis (PrEP) uptake and evaluate the degree to which substance use and, separately, the participant's intention to test affect HIV self-testing and PrEP uptake. Through this research, we will also examine how participants' social media use, attitudes on HIV testing, perceptions of sexual risk behavior, medical mistrust, and stigma impact HIV testing and PrEP uptake.

Conditions

HIV Infections

Keywords

HIV; Pre-exposure prophylaxis; Social media; Online advertising

Outcome Measures

Primary Outcomes (1)

• Self-test kit orders

  The daily rate (number of study participants per day) requesting an HIV home self-test kit by promotional platform (social media, informational, dating sites).

  60 days

Secondary Outcomes (1)

• Self-test kit use

  60 days

Study Arms (3)

Social media sites.

These participants will be recruited from advertisements posted on social media websites. Participants who complete the baseline assessment will receive a code to order a free HIV self-test kit. Participants will be asked to complete two online follow-up questionnaires at 14-days and 60-days post-baseline. These questionnaires will ask questions related to HIV self-test kit use and PrEP uptake.

Informational sites

These participants will be recruited from advertisements posted on informational websites. Participants who complete the baseline assessment will receive a code to order a free HIV self-test kit. Participants will be asked to complete two online follow-up questionnaires at 14-days and 60-days post-baseline. These questionnaires will ask questions related to HIV self-test kit use and PrEP uptake.

Dating applications

These participants will be recruited from advertisements posted on dating applications. Participants who complete the baseline assessment will receive a code to order a free HIV self-test kit. Participants will be asked to complete two online follow-up questionnaires at 14-days and 60-days post-baseline. These questionnaires will ask questions related to HIV self-test kit use and PrEP uptake.

Eligibility Criteria

• Age: 18 Years - 30 Years
• Gender Eligibility Details: This study will be recruiting individuals who were biologically born male and identify as men.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

This study is recruiting men who have sex with men who actively use social media sites, dating apps, or informational sites.

You may qualify if:

• Have clicked on one of the study-specific advertisements posted on the platforms/ websites;
• Have been biologically born male (cis-gender man), per participant self-report;
• Report condomless anal intercourse and more than one male sex partner in the 90 days prior to the date of the screening questionnaire;
• Be between the ages of 18-30 years old, inclusive;
• Self-identify as Latino and/or Black/African American;
• Not currently on PrEP and haven't taken PrEP in the last six months prior to the date of the screening questionnaire (per participant self-report);
• Have not tested for HIV in the last 3 months prior to the date of the screening questionnaire (per participant self-report);
• Have a Facebook account (for identity validation to reduce duplicate attempts at enrollment); and
• Be willing to provide contact information (phone number, email) to the study team.

You may not qualify if:

• Are unwilling or unable to provide informed consent.
• Are unwilling to provide contact information (phone number, email address).
• Report having a preliminary positive or positive HIV result in a test completed less than 30 days prior to the date of screening or report being currently under treatment for HIV infection.

Sponsors & Collaborators

• Lisa A. Marsch: lead
• National Drug Abuse Treatment Clinical Trials Network: collaborator
• University of California, Los Angeles: collaborator
• Dartmouth College: collaborator
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

UCLA David Geffen School of Medicine

Los Angeles, California, 90024, United States

Location

Related Publications (2)

• Stafylis C, Vavala G, Wang Q, McLeman B, Lemley SM, Young SD, Xie H, Matthews AG, Oden N, Revoredo L, Shmueli-Blumberg D, Hichborn EG, McKelle E, Moran LM, Jacobs P, Marsch LA, Klausner JD. Relative Effectiveness of Social Media, Dating Apps, and Information Search Sites in Promoting HIV Self-testing: Observational Cohort Study. JMIR Form Res. 2022 Sep 23;6(9):e35648. doi: 10.2196/35648.

  PMID: 36149729 DERIVED

• Lemley SM, Klausner JD, Young SD, Stafylis C, Mulatya C, Oden N, Xie H, Revoredo L, Shmueli-Blumberg D, Hichborn E, McKelle E, Moran L, Jacobs P, Marsch LA. Comparing Web-Based Platforms for Promoting HIV Self-Testing and Pre-Exposure Prophylaxis Uptake in High-Risk Men Who Have Sex With Men: Protocol for a Longitudinal Cohort Study. JMIR Res Protoc. 2020 Oct 19;9(10):e20417. doi: 10.2196/20417.

  PMID: 33074164 DERIVED

MeSH Terms

Conditions

HIV Infections

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Study Officials

• Jeffrey D. Klausner, MD

  University of California, Los Angeles

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 5, 2019
• First Posted: November 7, 2019
• Study Start: January 6, 2020
• Primary Completion: September 20, 2020
• Study Completion: September 25, 2020
• Last Updated: December 17, 2020

Record last verified: 2020-12

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: Data will be provided to NIDA CCTN-designated parties for posting on the NIDA Data Share website after completion of the study and data lock.
• Access Criteria: Per the NIDA Data Share 2.0 website: "Prior to downloading any study data, the user will be prompted to complete a registration agreement for data use. Users will have to register a name and valid e-mail address in order to download data and to accept their responsibility for using data in accordance with the NIDA Data Share Agreement."

Locations

US (1)