NCT04151797

Brief Summary

In patients aged 75 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy coupled with a lack of proactive elderly care can sometimes lead to hospitalisation. Due to comorbidities and complex problems, management of geriatric patients usually requires a multidisciplinary approach. In Toulouse University Hospital, elderly inpatients can benefit from a geriatric assessment by a Geriatric Mobile Team. Whether this team improve the prescriptions through the advice of a clinical pharmacist has not been demonstrated yet.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 15, 2019

Completed
21 days until next milestone

First Posted

Study publicly available on registry

November 5, 2019

Completed
14 days until next milestone

Study Start

First participant enrolled

November 19, 2019

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 22, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 22, 2021

Completed
Last Updated

November 28, 2025

Status Verified

May 1, 2021

Enrollment Period

1.3 years

First QC Date

October 15, 2019

Last Update Submit

November 21, 2025

Conditions

Medication Therapy Management

Keywords

Medication reviewclinical pharmacypolypharmacyolder peoplecollaborationinappropriate prescribing

Outcome Measures

Primary Outcomes (1)

  • Change from baseline patients' number of potentially inappropriate prescription at the patient discharge after optimization by a mobile geriatric team with pharmacist

    number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (at the patient discharge)

    Month 0 and max Month 2 (At the patient discharge)

Secondary Outcomes (9)

  • Change from baseline patients' number of potentially inappropriate prescription at 3 months after optimization by a mobile geriatric team with pharmacist

    Month 0, Month 3

  • Change from baseline patients' number with at least one potentially inappropriate drug at 3 months after optimization by a mobile geriatric team with pharmacist

    Month 0, Month 3

  • Change from baseline ratio of potentially inappropriate drug per patient at 3 months after optimization by a mobile geriatric team with pharmacist

    Month 0, Month 3

  • Change from baseline mean number of medications per patient at 3 months

    Month 0, Month 3

  • realisation of a pharmacist-led medication review in primary care

    Month 3

  • +4 more secondary outcomes

Study Arms (1)

Medication therapy management

EXPERIMENTAL

Medication therapy management by pharmacist-led medication review

Other: Medication therapy management

Interventions

Medication therapy managementOTHER

The intervention is in the form of a pharmacist-led medication review aimed at detecting potentially inappropriate prescribing. It includes: * Data collection on comorbidities, medication and laboratory results. * A pharmacist's evaluation of the prescriptions based on the patient's conditions and on the current recommendations for clinical practice. * A detailed feedback to the geriatrician. * A written report addressed to the attending physician

Medication therapy management

Eligibility Criteria

Age75 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patient aged 75 or older
  • Having 5 medications or more per day
  • Being hospitalised either in emergency room, short-stay medicine unit or surgery department

You may not qualify if:

  • Patient refuses to participate
  • Patient already included in another study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Toulouse University Hospital

Toulouse, Occitanie, 31059, France

Location

Related Publications (1)

  • Pages A, Roland C, Qassemi S, Abdeljalil AB, Houles M, Romain M, Toulza O, Belloc A, McCambridge C, Voisin T, Cestac P, Juillard-Condat B; PharMoG study group. Impact of a Pharmacist-included Mobile Geriatrics team intervention on potentially inappropriate drug prescribing: protocol for a prospective feasibility study (PharMoG study). BMJ Open. 2020 Dec 2;10(12):e040917. doi: 10.1136/bmjopen-2020-040917.

    PMID: 33268421BACKGROUND

MeSH Terms

Interventions

Medication Therapy Management

Intervention Hierarchy (Ancestors)

Pharmaceutical ServicesHealth ServicesHealth Care Facilities Workforce and ServicesMedicare Part DInsurance, Pharmaceutical ServicesInsurance, HealthInsuranceFinancing, OrganizedEconomicsHealth Care Economics and OrganizationsMedicarePatient Care ManagementHealth Services Administration

Study Officials

  • Philippe CESTAC, PharmD, PhD

    University Hospital, Toulouse

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 15, 2019

First Posted

November 5, 2019

Study Start

November 19, 2019

Primary Completion

March 22, 2021

Study Completion

March 22, 2021

Last Updated

November 28, 2025

Record last verified: 2021-05

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)