Exercise Intervention for Cancer Patients

NCT04151238 | Completed

• 1 other identifier: T306/2019
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

Exhausting chemotherapy, adverse effects of chemotherapy and a lack of information on the benefits of physical exercise are the among the reasons for reduced physical exercise among cancer patients during chemotherapy courses. According to best current knowledge only about 10% of cancer patients in Finland are physically active during cancer treatment. In addition, only 20-30% are physically active after recovery from the treatments (Pylkkänen, 2015). There is only little awareness about the benefits of physical activity during cancer treatments. The purpose of the exercise intervention study is to increase the physical activity of patients who are on chemotherapy. The study is a pilot trial and has no control group. Internationally, exercise interventions have been studied among cancer patients on treatment for decades. The American College of Sports Medicine (ACSM) recommends that cancer patients should have 150 minutes of endurance exercise per week and at least two bouts of muscle strength exercise per week. Consequently, the exercise intervention study will have a combination of muscle power and endurance training. To reach the weekly recommended level of exercise, the cancer patients in the study will additionally have a weekly home training program containing preferentially endurance training. A literature search shows that no studies on exercise interventions during cancer treatment have been published in Finland. Thus, this thesis carries the wider implication of increasing the general knowledge on the importance of physical activity of cancer patients.

Conditions

Cancer

Outcome Measures

Primary Outcomes (2)

• physical activity changes in diary

  Does this exercise intervention model works for cancer patients to increase the amount of physical activity and to achieve the cancer patients exercise recommendations? (especially home-exercising)

  0 and 8 weeks,

• questionnaire-feedback from cancer patients

  Does this exercise intervention model works for cancer patients to change the amount of physical activity? Patients subjective feedback about the first exercise group model in special health care. The questions are formed in quantitative way.

  0 and 8 weeks

Secondary Outcomes (10)

• Quality of life questionnaire (EORTC QLQ-c30)

  0 and 8 weeks

• Fatigue questionnaire (FACIT-F)

  0 and 8 weeks

• Body composition in cancer patients general view (In-Body-device)

  0 and 8 weeks

• Endurance (submaximal treadmill test)

  0 and 8 weeks

• Functional muscle power test - dynamic elevation test for upper arms

  0 and 8 weeks

Study Arms (1)

Exercise intervention

EXPERIMENTAL

The duration of the exercise intervention is eight (8) weeks. There will be guided endurance and muscle power training two (2) time weekly. The participants will also be provided with one training program per week for use at home. Data on training at home and other items of physical activity is recorded in a diary.

Behavioral: Exercise intervention for cancer patients to increase physical activity during chemotherapy

Interventions

Exercise intervention for cancer patients to increase physical activity during chemotherapy BEHAVIORAL

The duration of the exercise intervention is eight (8) weeks. There will be guided endurance and muscle power training two (2) time weekly. The participants will also be provided with one training program per week for use at home.

Exercise intervention

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• cancer patients in the age of 18-70
• in the early phase of chemotherapy
• first line chemotherapy
• active way of treating cancer
• solid tumor (breast cancer, prostata cancer, colon cancer and melanoma)
• Finnish-speaking
• z=0-1 (no aids)
• capable travelling to University hospital for 8 weeks twice a week
• normal or poor physical activity background

You may not qualify if:

• exercise contraindications, like severe respiratory or circulatory system disease (eg. heart attack \<3)
• brain or bone metastasis
• heterogenous group (max 4 patients per cancer diagnose)
• thrombocytopenia
• leukocytopenia
• immuno-oncological treatments
• really "athlete patients"

Sponsors & Collaborators

• Turku University Hospital: lead
• Turku AMK Master School: collaborator

Study Sites (1)

Turku University hospital

Turku, 20521, Finland

Location

MeSH Terms

Conditions

Neoplasms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 14, 2019
• First Posted: November 5, 2019
• Study Start: February 17, 2020
• Primary Completion: April 16, 2020
• Study Completion: May 8, 2020
• Last Updated: November 2, 2022

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share

Locations

FI (1)