NCT04144699

Brief Summary

The WheezeScan sensitivity and specificity are set to statistically prove equal to or higher values than the predicate PulmoTrack device model 2020.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
240

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2019

Typical duration for all trials

Geographic Reach
1 country

15 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 28, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 30, 2019

Completed
2 days until next milestone

Study Start

First participant enrolled

November 1, 2019

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

September 17, 2021

Status Verified

September 1, 2021

Enrollment Period

2.1 years

First QC Date

October 28, 2019

Last Update Submit

September 10, 2021

Conditions

Keywords

wheezerhonchus

Outcome Measures

Primary Outcomes (1)

  • Evaluate the sensitivity and specificity of the Omron WheezeScan device

    The WheezeScan device will be compared to the gold standard, auscultation, which will be performed by a physician or a qualified healthcare professional with a minimum of 3 years' experience. All breath sounds will be recorded for comparison in case of discrepancy.

    Novemver 1, 2019 ~ November 30, 2021

Study Arms (8)

Wheezing 3~11months

Patient has wheezing, age 3 to 11 months

Wheezing 12~23months

Patient has wheezing, age 12 to 23 months

Wheezing 24~35months

Patient has wheezing, age 24 to 35 months

Wheezing 36~107months

Patient has wheezing, age 36 to 107 months

No wheezing 3~11months

Patient do not have wheezing, age 3 to 11 months

No wheezing 12~23months

Patient do not have wheezing, age 12 to 23 months

No wheezing 24~35months

Patient do not have wheezing, age 24 to 35 months

No wheezing 36~107months

Patient do not have wheezing, age 36 to 107 months

Eligibility Criteria

Age3 Months - 8 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Wheezing Total : Min.120, Wheezing 3\~11months : Min.19, Wheezing 12\~23months : Min.19, Wheezing 24\~35months : Min.19, Wheezing 36\~107months : Min.38, No wheezing total : Min.120, No wheezing 3\~11months : Min.19, No wheezing 12\~23months : Min.19, No wheezing 24\~35months : Min.19, No wheezing 36\~107months : Min.38

You may qualify if:

  • Mild to moderate diagnosed or suspected asthma, bronchitis, or bronchiolitis patients who meet all of the following criteria are considered as eligible.
  • Does the subject have mild to moderate diagnosed or suspected asthma, bronchitis, or bronchiolitis?
  • Is the subject between the ages of 3 months to 8 years old?
  • Is the parent or legal guardian available, and capable and willing to give a consent on the child's behalf.

You may not qualify if:

  • The subjects will be excluded from the study, if they have any of the following criteria.
  • Does the subject have skin rashes or wounds on the chest?
  • Does the subject have known allergies or irritant contact dermatitis or having hypersensitive skin?
  • Does the subject have a defibrillator and/or pacemaker (which could interfere with the sounds to be detected)?
  • Does the subject have an allergy to disinfecting alcohol?
  • Does the subject have wheezes caused by not asthma, such as reflux esophagitis, pneumonia, vocal cord dysfunction, Tracheomatosis?
  • Does the subject have a heavy runny nose?
  • Is it difficult to hear auscultation due to the subject fussing, crying or vocalizing at data collection?
  • Is the subject having difficulty breathing or having severe symptoms?
  • Was the subject enrolled more than once for the same resulted breath sounds?
  • Note: The subject maybe enrolled once per arm (once wheezing, once non-wheezing).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (15)

Tekton Research

Chamblee, Georgia, 30341, United States

COMPLETED

University of Chicago

Chicago, Illinois, 60637, United States

RECRUITING

PMG Research of DuPage

Joliet, Illinois, 60435, United States

COMPLETED

Long Island Jewish Medical Center

New York, New York, 11042, United States

RECRUITING

PMG Research of Raleigh

Raleigh, North Carolina, 27609, United States

COMPLETED

PMG Research of Winston-Salem

Winston-Salem, North Carolina, 27103, United States

RECRUITING

Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

RECRUITING

PMG Research of Charleston

Charleston, South Carolina, 29403, United States

COMPLETED

Meridian Clinical Research, LLC

Dakota Dunes, South Dakota, 57049, United States

COMPLETED

PMG Research of Bristol

Bristol, Tennessee, 37620, United States

COMPLETED

PMG Research of Knoxville

Jefferson City, Tennessee, 37760, United States

COMPLETED

Tekton Research

Beaumont, Texas, 77706, United States

RECRUITING

Tekton Research

San Antonio, Texas, 78240, United States

COMPLETED

Tekton Research

San Antonio, Texas, 78258, United States

RECRUITING

University of Wisconsin

Madison, Wisconsin, 53792, United States

RECRUITING

MeSH Terms

Conditions

BronchitisBronchiolitisRespiratory Sounds

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2019

First Posted

October 30, 2019

Study Start

November 1, 2019

Primary Completion

November 30, 2021

Study Completion

December 31, 2021

Last Updated

September 17, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

No plan to share the data

Locations