NCT04144361

Brief Summary

three hundred morbidly obese patients candidate for sleeve gastrectomy will divided into equal two groups, group A : will operated by standard sleeve gastrectomy on bougie 36 without plication of stable line and group B: will operated by sleeve gastrectomy on bougie 42 with plication of stable line. the aim is to test the effect of pilcation on the incidence of leaks and bleeding

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 20, 2019

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 30, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

December 27, 2019

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 20, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 20, 2020

Completed
Last Updated

March 30, 2021

Status Verified

March 1, 2021

Enrollment Period

8 months

First QC Date

October 20, 2019

Last Update Submit

March 28, 2021

Conditions

Keywords

post sleeve gastrectomy leakpost sleeve gastrectomy

Outcome Measures

Primary Outcomes (2)

  • the incidence of postoperative stable line bleeding

    early postoperative bleeding from stable line

    2-24 hours

  • the incidence of stable line leakage

    leak from stable line

    1-30 days

Study Arms (2)

sleeve without plication

EXPERIMENTAL

sleeve gastrectomy on bougie 36 without plication

Procedure: sleeve without plication

sleeve with plication

ACTIVE COMPARATOR

sleeve gastrectomy on bougie 42 without plication

Procedure: sleeve with plication

Interventions

sleeve with plication

sleeve with plication

sleeve without plication

sleeve without plication

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • obese patients with BMI more than 40 with or without co-morbidity or more than 35 with co-morbidity
  • patients fit for laparoscopic surgery
  • give approval to share in the study

You may not qualify if:

  • patients refused to share in the study
  • patients unfit for surgery
  • patients aged less than 18 and older than 60
  • patient with previous upper abdominal surgery either for obesity or other diseases
  • revisional bariatric procedures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Faculty of medicine

Minya, 61511, Egypt

Location

Minya university hospital

Minya, 61511, Egypt

Location

MeSH Terms

Conditions

Obesity, Morbid

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • alaa M Sewefy

    Minia University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor and consultant of general surgery

Study Record Dates

First Submitted

October 20, 2019

First Posted

October 30, 2019

Study Start

December 27, 2019

Primary Completion

August 20, 2020

Study Completion

August 20, 2020

Last Updated

March 30, 2021

Record last verified: 2021-03

Locations