Imposed Pursed Lip Breathing at Rest and During Exercise In COPD

NCT04138069 | Completed DMC

• 1 other identifier: REC/00228 Madeeha Shafeeq
• Study Type: interventional
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

A randomized control trial was conducted at physiotherapy department of Pakistan Railway General Hospital from July 2017 to Dec 2017. 30 patients with stable COPD were enrolled in the study on the basis of inclusion and exclusion criteria. The participants were randomly assigned into two groups, Group A= interventional group, Group B = control group through toss and coin method using non-probability convenient sampling technique and written consent was obtained from each patient participated in the study. From 30 patients 15 patients were randomly allocated to each group, Group A: Interventional (n= 15), Group B: Control (n=15). 1 patient in control group B was dropout because he didn't come for follow up. Overall 29 patients were evaluated for study as in Group A, interventional (n=15) and Group B control (n=14).Patients in group A were performed breathing control at the start of session and then Purse lips breathing technique during aerobic bicycling for 8 min while in group B patients first perform breathing control and then aerobic bicycling for 8 min. Subjects in both experimental and control group underwent spirometry and baseline vitals, such as Respiratory rate, blood pressure, and oxygen saturation, at rest and at the completion of session was noted. Borg scale of dyspnea also used to rate the level of dyspnea at rest and at the end of session. Clinical COPD Questionnaire (CCQ) was used at 1st and final week of evaluation. It was 6 weeks training protocol, with three days per week session was given to the patient.

Conditions

COPD

Keywords

COPD; Pursed Lips Breathing; Dyspnea; Pulmonary Function Test (PFT); Aerobic Training

Outcome Measures

Primary Outcomes (3)

• Forced Expiratory Volume in 1 second (FEV1)

  Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters

  6th week

• Forced vital Capacity (FVC)

  Changes From the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters.

  6th week

• Peak Expiratory Flow (PEF)

  Changes from the Baseline, the digital spirometer is used in clinical setting to analyze peak expiratory flow PEF in Liter/second.

  6th week

Secondary Outcomes (1)

• Breathing Pattern

  6th weeks

Study Arms (2)

PLB+Aerobic Bicycling

EXPERIMENTAL

Pursed Lip Breathing + Aerobic Bicycling

Other: PLB+Aerobic Bicycling

Aerobic Bicycling

ACTIVE COMPARATOR

Only Aerobic bicycling

Other: Aerobic Bicycling

Interventions

PLB+Aerobic Bicycling OTHER

Combination of Breathing control and Purse lips breathing technique for 5 minutes at the start of session. Purse lips breathing with aerobic bicycling for 8 minutes

PLB+Aerobic Bicycling

Aerobic Bicycling OTHER

Breathing control for 5 minutes at the start of session. Aerobic bicycling for 8 minutes

Aerobic Bicycling

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• COPD stage 2 and 3 patients \[based on "Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria\]

You may not qualify if:

• neurological disorder and
• cardiovascular disorder
• Impaired lower limbs mobility

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Imran Amjad

Islamabad, Punjab Province, 44000, Pakistan

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Dyspnea

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms

Study Officials

• Iqbal Tariq, MsCPPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 22, 2019
• First Posted: October 24, 2019
• Study Start: July 1, 2017
• Primary Completion: December 25, 2017
• Study Completion: December 30, 2017
• Last Updated: January 13, 2020

Record last verified: 2020-01

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)