MultiOrgan Multi-Parametric MRI Study
MORIS
1 other identifier
observational
43
1 country
3
Brief Summary
To determine the reproducibility of a single quantitative multiparametric MRI for the assessment of body composition and multiple organ structures.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Nov 2019
Longer than P75 for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 22, 2019
CompletedFirst Posted
Study publicly available on registry
October 24, 2019
CompletedStudy Start
First participant enrolled
November 4, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 25, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
November 25, 2023
CompletedDecember 1, 2025
November 1, 2025
4.1 years
October 22, 2019
November 27, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Assessment of repeatability (precision under the same conditions in the same subjects: 2 separate MRI acquisitions on the same scanner) of body composition and multiple organ metrics.
To determine the repeatability of multiparametric MRI in the assessment of body composition and multiple organ structures obtained within a single MR scanning session (liver, pancreas, aorta, heart, kidney, lungs and spleen)
24 months
Secondary Outcomes (1)
Assessment of the reproducibility (precision under different measurement conditions: same participants scanned on separate MRI scanners at both 1.5T and 3T) of multiparametric MRI for the assessment of body composition and multiple organ metrics.
24 months
Other Outcomes (1)
Assessment of the mean differences in body composition and multiple organ metrics between healthy participants and those with type 2 diabetes acquired with multiparametric MRI.
24 months
Interventions
A standardised MRI protocol that provides a number of quantitative metrics on liver and other organs relevant to type 2 Diabetes - pancreas, kidneys, spleen, heart, lungs and aorta
Eligibility Criteria
Adult volunteers, including healthy volunteers and individuals with Type 2 Diabetes (T2D).
You may qualify if:
- Any person over 18 years of age.
- Participant is willing and able to give informed consent for participation in the investigation.
- EITHER: Participant has Type 2 Diabetes OR: Person is a healthy volunteer
You may not qualify if:
- The participant may not enter the investigation if they have any contraindication to magnetic resonance imaging (incl. pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia).
- Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the investigation, or may influence the result of the investigation, or the participant's ability to participate in the investigation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Perspectumlead
Study Sites (3)
Beaver House
Oxford, OX1 2EH, United Kingdom
Oxford Centre for Magnetic Resonance
Oxford, OX3 9DU, United Kingdom
Gemini One
Oxford, OX4 2LL, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Rajarshi Banerjee
Perspectum
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 22, 2019
First Posted
October 24, 2019
Study Start
November 4, 2019
Primary Completion
November 25, 2023
Study Completion
November 25, 2023
Last Updated
December 1, 2025
Record last verified: 2025-11