NCT04135950

Brief Summary

The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. This study is a registry of all patients having knee surgery at our institution performed by 4 fellowship-trained orthopaedic surgeons. The surgeon documents patient information on standard data forms including risk factors and surgical findings.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,646

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2005

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
14.8 years until next milestone

First Submitted

Initial submission to the registry

October 21, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 23, 2019

Completed
6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 28, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 28, 2025

Completed
Last Updated

November 20, 2025

Status Verified

November 1, 2025

Enrollment Period

20.8 years

First QC Date

October 21, 2019

Last Update Submit

November 18, 2025

Conditions

Anterior Cruciate Ligament TearMeniscal TearCartilage InjuryBone Bruising

Outcome Measures

Primary Outcomes (1)

  • additional injury

    At the time of ACL surgery, it is determined if the patient has any other injuries to the meniscus or cartilage.

    intraoperatively

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients at our institution who are having ACL surgery by one of 4 fellowship-trained surgeons will be included in this registry.

You may qualify if:

  • Patients undergoing ACL surgery

You may not qualify if:

  • Previous surgery on the affected knee
  • Posterior cruciate ligament injuries
  • Grade 2 lateral collateral ligament or medial collateral ligament injuries

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UBMD Orthopaedics and Sports Medicine

Buffalo, New York, 14226, United States

Location

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee InjuriesLeg InjuriesWounds and Injuries

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
20 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
June A. and Eugene R. Mindell, MD Professor and Chair

Study Record Dates

First Submitted

October 21, 2019

First Posted

October 23, 2019

Study Start

January 1, 2005

Primary Completion

October 28, 2025

Study Completion

October 28, 2025

Last Updated

November 20, 2025

Record last verified: 2025-11

Locations

US(1)