NCT04132934

Brief Summary

The purpose of this observational study is to assess effectiveness and tolerability of gliclazide MR 60mg during RAMADAN in a real world setting in 9 countries from Asia Pacific and Middle East/North Africa

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 11, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 4, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 4, 2019

Completed
12 days until next milestone

First Submitted

Initial submission to the registry

October 16, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 21, 2019

Completed
Last Updated

June 5, 2020

Status Verified

June 1, 2020

Enrollment Period

7 months

First QC Date

October 16, 2019

Last Update Submit

June 3, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Proportion of patients with at least one Hypoglycemia event

    up to 5 months

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with type 2 diabetes observing fast during Ramadan

You may qualify if:

  • Informed consent obtained before any trial-related activities
  • Male or female type 2 diabetic patients aged \>18 years
  • Patients with controlled or suboptimal controlled type 2 diabetes
  • Patients with experience in SMBG controlling using glucometer
  • Patients who are willing to fast during Ramadan
  • Patients already treated with Gliclazide MR 60mg

You may not qualify if:

  • Insulin therapy requirement
  • Severe liver or renal failure
  • HbA1c ≥ 9%
  • Contraindication to gliclazide according to SmPC
  • Pregnancy or breast feeding
  • Previous experience of severe or repeated hypoglycemia events without triggered factor within the previous year

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Servier Affaires Medicales

Suresnes, 92284, France

Location

Related Publications (2)

  • Hassanein M, Al Sifri S, Shaikh S, Abbas Raza S, Akram J, Pranoto A, Rudijanto A, Shaltout I, Fariduddin M, Mohd Izani Wan Mohamed W, Al Awadi F, Alessa T; DIA-RAMADAN study investigators. A real-world study in patients with type 2 diabetes mellitus treated with gliclazide modified-release during fasting: DIA-RAMADAN. Diabetes Res Clin Pract. 2020 May;163:108154. doi: 10.1016/j.diabres.2020.108154. Epub 2020 Apr 21.

  • Hassanein M, Al Sifri S, Shaikh S, Raza SA, Akram J, Rudijanto A, Shaltout I, Fariduddin M, Mohamed WMIBW, Al Awadi F, Durocher A, Cortese V, Alessa T. Descriptive Regional Subanalysis of a Real-World Study in Patients with Type 2 Diabetes Treated with Gliclazide MR During Fasting: DIA-RAMADAN. Diabetes Ther. 2021 Jun;12(6):1703-1719. doi: 10.1007/s13300-021-01067-1. Epub 2021 May 11.

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 16, 2019

First Posted

October 21, 2019

Study Start

March 11, 2019

Primary Completion

October 4, 2019

Study Completion

October 4, 2019

Last Updated

June 5, 2020

Record last verified: 2020-06

Locations