Prediction of Failure of Dental Implants

NCT04129957 | Completed

• 1 other identifier: 2018.376
• Study Type: observational
• Target: 337
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to identify predictors in patient profiles and implant characteristics and to develop and calibrate a prediction model for failure of implants. Patients' demographic characteristics, lifestyle habits, general health, dental health, and implant characteristics were regarded as potential predictors. The failure of implants and the follow-up time in days of implants were considered the outcome. Multivariate Cox proportional hazards regression analysis is used to find out the important risk factors for failure of dental implants and to develop the model for prediction of failure of dental implants at follow-up. The performance and clinical values of the model is determined.

Conditions

Implant Complication; Peri-Implantitis

Keywords

prediction; dental implants; failure; peri-implantitis

Outcome Measures

Primary Outcomes (2)

• Failure of dental implants

  The failure of implants was defined as the presence of peri-implantitis, presence of mobility of implants, or removal of the implants for any reasons, for instance, unacceptable performance in aspects of function, tissue physiology, esthetics, and patients' satisfaction after placement of suprastructure.

  up to 5 years follow-up

• Follow-up time

  The follow-up time is defined as the difference in time between implant placement and implant failure, or the date of the last follow-up time point if the dental implant is in an acceptable state.

  up to 5 years follow-up

Study Arms (1)

Patients who underwent placement of dental implants

The study only includes one cohort. That is the patients who underwent placement of dental implants at baseline.

Procedure: Placement of dental implants

Interventions

Placement of dental implants PROCEDURE

All the included patients underwent the placement of at least one implant in either upper jaw, or lower jaw, or both.

Also known as: No other intervention

Patients who underwent placement of dental implants

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The included patients were those who were referred to the Department of Oral Implantology and Prosthetic Dentistry, ACTA for placement of implant(s).

You may qualify if:

• patients were over 18 years old at baseline;
• patients underwent the placement of at least one implant;
• patients were followed up for the implants at least one time after placement of implants;
• patients provided their informed consent.

You may not qualify if:

• patients were \<18 years old at baseline;
• patients were not followed up;
• patients did not provide the informed consent.

Sponsors & Collaborators

• Academic Centre for Dentistry in Amsterdam: lead

Study Sites (1)

Academic Centre for Dentistry in Amsterdam

Amsterdam, North Holland, 1081LA, Netherlands

Location

Related Publications (6)

• Pjetursson BE, Thoma D, Jung R, Zwahlen M, Zembic A. A systematic review of the survival and complication rates of implant-supported fixed dental prostheses (FDPs) after a mean observation period of at least 5 years. Clin Oral Implants Res. 2012 Oct;23 Suppl 6:22-38. doi: 10.1111/j.1600-0501.2012.02546.x.

  PMID: 23062125 BACKGROUND

• Pjetursson BE, Asgeirsson AG, Zwahlen M, Sailer I. Improvements in implant dentistry over the last decade: comparison of survival and complication rates in older and newer publications. Int J Oral Maxillofac Implants. 2014;29 Suppl:308-24. doi: 10.11607/jomi.2014suppl.g5.2.

  PMID: 24660206 BACKGROUND

• Jung RE, Zembic A, Pjetursson BE, Zwahlen M, Thoma DS. Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years. Clin Oral Implants Res. 2012 Oct;23 Suppl 6:2-21. doi: 10.1111/j.1600-0501.2012.02547.x.

  PMID: 23062124 BACKGROUND

• Krebs M, Schmenger K, Neumann K, Weigl P, Moser W, Nentwig GH. Long-term evaluation of ANKYLOS(R) dental implants, part i: 20-year life table analysis of a longitudinal study of more than 12,500 implants. Clin Implant Dent Relat Res. 2015 Jan;17 Suppl 1:e275-86. doi: 10.1111/cid.12154. Epub 2013 Sep 17.

  PMID: 24103113 BACKGROUND

• Lekholm U, Grondahl K, Jemt T. Outcome of oral implant treatment in partially edentulous jaws followed 20 years in clinical function. Clin Implant Dent Relat Res. 2006;8(4):178-86. doi: 10.1111/j.1708-8208.2006.00019.x.

  PMID: 17100743 BACKGROUND

• Ostman PO, Hellman M, Sennerby L. Ten years later. Results from a prospective single-centre clinical study on 121 oxidized (TiUnite) Branemark implants in 46 patients. Clin Implant Dent Relat Res. 2012 Dec;14(6):852-60. doi: 10.1111/j.1708-8208.2012.00453.x. Epub 2012 May 29.

  PMID: 22642261 BACKGROUND

MeSH Terms

Conditions

Peri-Implantitis

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Study Officials

• Geert van der Heijden, Prof. dr.

  Academic Centre for Dentistry Amsterdam

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 15, 2019
• First Posted: October 17, 2019
• Study Start: December 10, 2018
• Primary Completion: June 30, 2019
• Study Completion: August 15, 2019
• Last Updated: October 21, 2019

Record last verified: 2019-10

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Starting 6 months after the publication. The data will be available for 15 years after the end of the study.
• Access Criteria: The data can be shared upon researchers' request via email (n.su@acta.nl). Naichuan Su will review the requests. The researchers need to share their protocols and guarantee that the data is only used for research purpose.

Locations

NL (1)