Heart Failure in Southern Sweden

NCT04129658 | Completed DMC

• 1 other identifier: 1111
• Study Type: observational
• Target: 563
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to optimize diagnosis and treatment for patients with heart failure in Swedish primary care. Patient with the diagnose heart failure registered in the electronic medical record (EMR) at seventeen primary health care centers (PHCCs) will be invited to to participate in the study. Blood testing and electrocardiography will be performed. Data on diagnosis and medical treatment will be collected from the EMR. An educational visit with a cardiologist will be performed at the PHCC, in order to discuss evidence-based diagnoses and treatment of heart failure. Data on drug therapy and health care consumption will be collected after six and twelve months.

Conditions

Heart Failure，Congestive; Drug Use; Patient Care

Outcome Measures

Primary Outcomes (1)

• Medication change

  Change in proportion of patients treated with the combination angiotensin conversion enzyme-inhibitors(ACEi) or angiotensin receptor blockers (ARB) and betablockers

  6 months after inclusion

Secondary Outcomes (4)

• Change in health care consumption

  One year after the intervention

• Change in mortality rate

  One year after the intervention

• Change in medication

  Six months after the intervention

• Change in diagnostics

  Six months after the intervention

Study Arms (2)

Intervention

The patients are registered at PHCCs who agreed to participate into the study, the patients have provided an informed consent. The PHCCs (seventeen according to the power calculation) will receive an educational outreach visit by a cardiologist, discussing evidence-based treatment. The physician will decide afterwords if the treatment will be adjusted. Blood samples and electrocardiography will be collected before the intervention, data from the EMR will be collected before and after the intervention.

Behavioral: Educational outreach visit

Control

The control group will be the rest of the patients with heart failure in Southern Sweden. Data from the regional data base on medication and heath care consumption will be collected at base line and 6 and 12 months after.

Interventions

Educational outreach visit BEHAVIORAL

Two-four hours of discussion between a cardiologist and the primary care physicians at the PHCC encompassing evidence-based treatment guidelines and counseling upon specific patient cases and their diagnose and treatment for congestive heart failure.

Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who meet the inclusion criteria and left informed consent, at Swedish PHCCs that have previously agreed to participate in the study. All invited PHCCs are located in the Region of Skane, Southern Sweden.

You may qualify if:

• patients with ICD diagnose I50, I11.0, I42 and I43 in the electronic medical journal and who have left informed consent to participate in the study

You may not qualify if:

• patients with ICD diagnose I42.1, I42.2
• patients where the heart failure diagnose is set on wrong grounds according to the information in the electronic medical journal, as normal NT-proBNP or/and normal ecocardiogram.

Sponsors & Collaborators

• Region Skane: lead

Study Sites (1)

Vårdcentralen Granen

Malmo, Sweden

Location

Related Publications (1)

• Svensson Soderberg K, Kronestedt Lundevall L, Lindow T, O Braun O, Smith JG, Sundquist K, Milos Nymberg V. Heart failure in Southern Sweden (HISS): a cross-sectional analysis of primary care patients' characteristics and physicians' adherence to guideline-directed medical therapy. BMJ Open. 2025 Nov 4;15(11):e101178. doi: 10.1136/bmjopen-2025-101178.

  PMID: 41248346 DERIVED

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 15, 2019
• First Posted: October 17, 2019
• Study Start: May 26, 2021
• Primary Completion: January 31, 2024
• Study Completion: January 31, 2024
• Last Updated: February 29, 2024

Record last verified: 2024-02

Locations

SE (1)