Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District

NCT04127682 | Completed

• 1 other identifier: AMR_PH01
• Study Type: observational
• Target: 186
• Locations: 1 country
• Sites: 1

Brief Summary

Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic resistance. It is important to study physicians' antibiotic prescribing behavior to understand its determinant and for further planning of appropriate interventions to optimize antibiotic prescription.

Conditions

Antibiotic Side Effect

Outcome Measures

Primary Outcomes (2)

• Physicians knowledge of antibiotic resistance

  By self administered questionnaire

  6 months

• Attitude and practice of physicians as regard antibiotic prescription in pediatric cases of acute upper respiratory tract infections.

  By self administered questionnaire

  6 months

Secondary Outcomes (1)

• Determinants of physicians' antibiotic prescribing behavior in cases of acute upper respiratory tract infection in children.

  6 months

Study Arms (1)

Physicians

Physicians dealing with cases of pediatrics' acute URIs at PHC units either urban or rural, insurance hospitals or Assiut university hospitals.

Other: Antibiotic KAP questionnaire

Interventions

Antibiotic KAP questionnaire OTHER

• Self-administered questionnaire will be used and containing following Physician information (age, sex, place of work, specialty, years of experience, place of work, and post graduate studies and trainings), Practice information (number of days for outpatient's practice/week, average number of patients /day and average percentage of children with ARIs/day), Antibiotic prescription practice (using of guidelines and causes of prescribing antibiotics in acute URIs), Knowledge about antibiotic resistance and attendance of any conference or educational activities concerned with antibiotic use during the last year, Attitude as regard antibiotic prescription.

Physicians

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Physicians dealing with cases of pediatrics' acute URIs at PHC units either urban or rural, insurance hospitals or Assiut university hospitals.

You may qualify if:

• Physicians dealing with pediatric cases.
• GPs, pediatrics, or otolaryngology (ENT) residents.

You may not qualify if:

• Physician who didn't work at outpatient clinics.
• Physicians who are specialized and hold a degree.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Faculty of medicine- Assiut university

Asyut, 71515, Egypt

Location

Related Publications (4)

• Tamma PD, Cosgrove SE. Let the games begin: the race to optimise antibiotic use. Lancet Infect Dis. 2014 Aug;14(8):667-668. doi: 10.1016/S1473-3099(14)70809-6. Epub 2014 Jul 9. No abstract available.

  PMID: 25022437 BACKGROUND

• Dooling KL, Kandeel A, Hicks LA, El-Shoubary W, Fawzi K, Kandeel Y, Etman A, Lohiniva AL, Talaat M. Understanding Antibiotic Use in Minya District, Egypt: Physician and Pharmacist Prescribing and the Factors Influencing Their Practices. Antibiotics (Basel). 2014 Jun 20;3(2):233-43. doi: 10.3390/antibiotics3020233.

  PMID: 27025746 BACKGROUND

• Meeker D, Linder JA, Fox CR, Friedberg MW, Persell SD, Goldstein NJ, Knight TK, Hay JW, Doctor JN. Effect of Behavioral Interventions on Inappropriate Antibiotic Prescribing Among Primary Care Practices: A Randomized Clinical Trial. JAMA. 2016 Feb 9;315(6):562-70. doi: 10.1001/jama.2016.0275.

  PMID: 26864410 BACKGROUND

• Amin MT, Abd El Aty MA, Ahmed SM, Elsedfy GO, Hassanin ES, El-Gazzar AF. Over prescription of antibiotics in children with acute upper respiratory tract infections: A study on the knowledge, attitude and practices of non-specialized physicians in Egypt. PLoS One. 2022 Nov 3;17(11):e0277308. doi: 10.1371/journal.pone.0277308. eCollection 2022.

  PMID: 36327297 RESULT

Study Officials

• Mahmoud A Abd El Aty

  Public Health Department, Faculty of Medicine, Assiut University

  STUDY DIRECTOR

• Sabra M Ahmed

  Public Health Department, Faculty of Medicine, Assiut University

  STUDY DIRECTOR

• Ghada O El-Sadafi

  Pediatrics department, Faculty of Medicine, Assiut University

  STUDY DIRECTOR

• Amira F El-Gazzar

  Public Health Department, Faculty of Medicine, Assiut University

  STUDY DIRECTOR

• Mariam T Amin

  Public Health Department, Faculty of Medicine, Assiut University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physician

Study Record Dates

• First Submitted: October 13, 2019
• First Posted: October 15, 2019
• Study Start: January 1, 2021
• Primary Completion: July 30, 2022
• Study Completion: October 30, 2022
• Last Updated: November 8, 2022

Record last verified: 2022-11

Locations

EG (1)