Trials Sponsors Conditions Drugs Pricing

Conditions

Blastocyst Disintegration

Keywords

blastocystVitrificationartificial collapsesurvival rate

Outcome Measures

Primary Outcomes (2)

survival rate
survival rate will be assessed immediately after thawing and compared between both groups.
immediately after thawing
survival rate
survival rate will be assessed at 140 minutes after thawing and compared between both groups.
140 min after thawing

Study Arms (2)

Study group (artificially laser-collapsed blastocysts)

EXPERIMENTAL

laser was used as an intervention before blastocyst vitrification to assist rapid blastocyst collapse with vitrification

Device: laser assisted collapse

& control group (blastocysts were vitrified, no laser collapse

NO INTERVENTION

blastocyst were vitrified without laser assisted collapse

Interventions

laser assisted collapseDevice

Apply 1-2 pulses of laser using the Saturn between 2 adjacent trophectoderm cells away from the inner cell mass in the blastocysts

Study group (artificially laser-collapsed blastocysts)

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age20 Years - 37 Years

Sexfemale(Gender-based eligibility)

Gender Eligibility Detailsblastocysts of infertile couples

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

Age limit 20-37 At least 6 good quality blastocysts per case. expansion rate 3-4

You may not qualify if:

Sponsors & Collaborators

Hawaa Fertility Center
Othercollaborator
Benha University
Otherlead

Study Sites (1)

Hawaa Fertility Center

Banhā, Qalyubia Governorate, 13512, Egypt

MeSH Terms

Conditions

Embryo Loss

Condition Hierarchy (Ancestors)

Abortion, SpontaneousPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesDeathPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

sahar A Eissa, Ph. D
HFC
PRINCIPAL INVESTIGATOR

Enrollment

10 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: TRIPLE
Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Masking Details: only the investigator knew the procedure provided for each case
Purpose: BASIC SCIENCE
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assistant professor of Obstetrics & Gynecology

Study Record Dates

First Submitted

October 8, 2019

First Posted

October 11, 2019

Study Stopped

Truth or Dare; Artificial Blastocoel Collapse Using Laser Before Blastocyst's Vitrification Versus Non-laser Usage

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (2)

Study group (artificially laser-collapsed blastocysts)

& control group (blastocysts were vitrified, no laser collapse

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (2)

Study group (artificially laser-collapsed blastocysts)

& control group (blastocysts were vitrified, no laser collapse

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations