NCT04124718|Completed
VDR and TFIP11 Gene Polymorphism and Gene-environmental Interaction in Adults
Association Between Enamel Gene Variants and Dental Caries in Adults
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Association Between Enamel Gene Variants and Dental Caries in Adults
Sponsor study identifier
observational
160
1 country
1
Study Start
December 26, 2019
Actual (reported)Primary Completion
January 26, 2020
Actual (reported)Study Completion
February 10, 2020
Actual (reported)VDR and TFIP11 Gene polymorphism and gene-environment interactions on caries etiology and susceptibility in adults.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 10, 2020
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 10, 2019
Actual (reported)October 11, 2019
Actual (reported)December 26, 2019
Actual (reported)January 26, 2020
Actual (reported)February 10, 2020
Actual (reported)past caries experience
Each tooth will be examined and recorded as decayed, missing, or filled
3 weeks
Plaque index
3 weeks
80 adults will be allowed in the high caries experience group according to DMFT index DMFT\>13.9
80 adults will be allowed in the high caries experience group according toDMFT index DMFT≤4
DNAs were obtained from epithelial cells in buccal mucosa and were extracted with Genomic DNA Isolation Kit
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
160 adult in the 24-40 age range living in Northeast Turkey will allowed in the study
Recep Tayyip Erdogan University Dentistry Faculty
Rize, 53000, Turkey (Türkiye)
Cogulu D, Onay H, Ozdemir Y, Aslan GI, Ozkinay F, Eronat C. The Role of Vitamin D Receptor Polymorphisms on Dental Caries. J Clin Pediatr Dent. 2016;40(3):211-4. doi: 10.17796/1053-4628-40.3.211.
DNA for genetic analysis was isolated from buccal epithelial cells
Gül Yıldız Telatar, dr
Recep Tayyip Erdogan University Dentistry Faculty
160 participants (actual enrollment reported by the registry).
First Submitted
October 10, 2019
First Posted
October 11, 2019
Study Start
December 26, 2019
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
January 26, 2020
Actual (reported)Study Completion
February 10, 2020
Actual (reported)Last Updated
April 15, 2021
Record last verified: 2021-04
Data will be available within 6 months of study completion
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Source: ClinicalTrials.gov.
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