NCT04121962

Brief Summary

The objectives of the study are to assess the feasibility, reach and preliminary efficacy of a brief intervention that trains Black men who have sex with men \[referred to as Index\] (a) to use home-based testing for HIV and sexually transmitted infections and (b) promote home-based testing to their peers and sexual partners.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
163

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 6, 2019

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 4, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 10, 2019

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2022

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 11, 2023

Completed
10 months until next milestone

Results Posted

Study results publicly available

May 20, 2024

Completed
Last Updated

May 20, 2024

Status Verified

May 1, 2024

Enrollment Period

2.8 years

First QC Date

October 4, 2019

Results QC Date

April 4, 2024

Last Update Submit

May 14, 2024

Conditions

Keywords

Black MSMSocial network

Outcome Measures

Primary Outcomes (3)

  • Session Attendance

    number of participants who completed 80%

    3 month

  • Number of Index Participants Who Requested Test Kits

    Number of Index participants who requested test kits is reported

    3 months

  • Number of Participants Who Return Kits for Testing

    Number of participants who returned kits to lab for testing is reported.

    3 month

Study Arms (2)

Peer Mentor

EXPERIMENTAL

Peer Mentor Training is 5 individual sessions with a 30 day check-in session. This condition is focused on training Index with communication skills to promote HIV and STI testing and treatment and pre-exposure prophalaxis (PrEP) to individuals in their social networks. Peer Mentor training is conducted by a one health educator. The sessions are held once a week and will last approximately 60 minutes.

Behavioral: Peer Mentor

Control

ACTIVE COMPARATOR

Is one individual-based session which will be conducted by sending a video about the website of a health educator.

Behavioral: Website only

Interventions

Peer MentorBEHAVIORAL

Participants will be trained to be Peer Mentors and promote home-based testing to their social network

Peer Mentor
Website onlyBEHAVIORAL

Participants will be given instructions on how to use the project website to request kits to test for HIV at home and collect specimens for lab testing.

Control

Eligibility Criteria

Age17 Years - 60 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsBiologic male who identifies as male
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • self-report male sex
  • condomless anal sex with \>1 male in the prior 6 months
  • self-report Black race
  • aged 18 or older
  • internet use at least once a week.

You may not qualify if:

  • younger than 17

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lighthouse Studies @ Peer Point

Baltimore, Maryland, 21205, United States

Location

Related Publications (1)

  • Tobin KE, Heidari O, Winiker A, Pollock S, Rothwell MD, Alexander K, Owczarzak J, Latkin C. Peer Approaches to Improve HIV Care Cascade Outcomes: a Scoping Review Focused on Peer Behavioral Mechanisms. Curr HIV/AIDS Rep. 2022 Aug;19(4):251-264. doi: 10.1007/s11904-022-00611-3. Epub 2022 Jul 7.

    PMID: 35798989BACKGROUND

MeSH Terms

Conditions

Acquired Immunodeficiency SyndromeSexually Transmitted Diseases

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Limitations and Caveats

This study occurred during the COVID-19 pandemic and amid the stay at home orders. Therefore recruitment was interrupted and the delivery of the intervention and control were remote. The stay-at home orders also disrupted the follow-up activities.

Results Point of Contact

Title
Dr. Karin Tobin
Organization
Johns Hopkins Bloomberg School of Public Health

Study Officials

  • Karin E Tobin, PhD

    Johns Hopkins Bloomberg School of Public Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2019

First Posted

October 10, 2019

Study Start

May 6, 2019

Primary Completion

March 9, 2022

Study Completion

July 11, 2023

Last Updated

May 20, 2024

Results First Posted

May 20, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will share

Investigators will share data in a way that will protect participant confidentiality. Within 12 months of publication of the primary papers for this study, a dataset of aggregate values will be made available. Due to the highly sensitive nature of the data collected and the characteristics of this often stigmatized population, no client-level data will be shared until the entire cohort is accrued and completed, even that which is de-identified; this will reduce the risk of small numbers resulting in deductive identification.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
12 months after data collection is over
Access Criteria
To Be Determined

Locations