Molecular Characterization of Candida Auris

NCT04121871 | Completed

• 1 other identifier: Oral Fungal Infection
• Study Type: observational
• Target: 384
• Locations: 1 country
• Sites: 2

Brief Summary

Candida auris is emerging fungal opportunistic pathogen in developing countries. Much studies has been conducted on Candida albicans. there was a dire need to investigate this alarming threat. Our hypothesis is that by recording the patients diagnosed with oropharygneal candidiasis and collecting clinical swab samples from these patients will be fruitful if microbiological isolation, identification and molecular characterization will be done. So this is the first study on C. auris in south punjab, Pakistan. Aim of this study is to collect epidemiological data of C. auris.

Conditions

Oral Fungal Infection

Keywords

Candida auris; Oral Fungal Infection; Candidiasis

Outcome Measures

Primary Outcomes (3)

• Prevalence of C. auris

  patients from selected localities will be recorded along with total patients in that category, prevalence will be calculated on the record collected from specified duration of study

  From November 15, 2019 to February 29, 2020

• Seasonality of C. auris infection

  Number of patients recorded during different months will be the source of calculation of seasonality index of the C. auris infection

  From November 15, 2019 to February 29, 2020

• Drug susceptibility

  Antifungal drug discs will be used for assessing the antfungal drugs susceptibility

  From November 15, 2019 to February 29, 2020

Interventions

No intervention OTHER

Not required

Eligibility Criteria

• Age: Up to 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All individuals are equally eligible to be selected in the study

You may qualify if:

• Pre-diagnosed Patients of both gender from pre-selected localities

You may not qualify if:

• Healthy individuals or individuals having no oral fungal infection individuals above 100 years of age

Sponsors & Collaborators

• Islamia University of Bahawalpur: lead

Study Sites (2)

Bahawal Victoria Hospital Bahawalpur

Bahawalpur, Punjab Province, 63100, Pakistan

Location

Civil Hospital Jhangi Wala Road Bahawalpur

Bahawalpur, Punjab Province, 63100, Pakistan

Location

Biospecimen

Retention: NONE RETAINED

Clinical oral swab samples from infected patients will be collected

MeSH Terms

Conditions

Candidiasis

Condition Hierarchy (Ancestors)

Mycoses; Bacterial Infections and Mycoses; Infections

Study Officials

• Jafi H Shirazi, M.Phil

  The Islamia University of Bahawalpur

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 7, 2019
• First Posted: October 10, 2019
• Study Start: November 15, 2019
• Primary Completion: February 29, 2020
• Study Completion: February 29, 2020
• Last Updated: October 27, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)