NCT04112485

Brief Summary

60 patients involved were divided into two matched groups; Group A: 30 patients were treated with conventional fenestration laminectomy and discectomy and Group B: 30 patients were treated with microdiscectomy. The age of the patients involved in this study ranged from 19 years old to 46 years old

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2015

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 4, 2015

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2019

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 20, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 27, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 2, 2019

Completed
Last Updated

May 11, 2020

Status Verified

May 1, 2020

Enrollment Period

4.5 years

First QC Date

September 27, 2019

Last Update Submit

May 8, 2020

Conditions

Keywords

Lumbar disc herniation , Open Discectomy, Micrdiscectomy

Outcome Measures

Primary Outcomes (2)

  • Visual analogue score

    Visual analogue score of back pain and leg pain which represent a score from 0-10 so if patient has no pain so gives 0 and if has severe pain gives 10

    Visua analogue score was assessed preoperatively and postoperatively to see how much change in pain can occurred after open discectomy and after Microdiscectomy for 1 year

  • Oswestry disability index

    Oswestry disability index in a measurement of functional ability of patients regarding pain and daily activities

    Oswestry disability index was assessed preoperatively and postoperatively to assess how much changes can occur after open discectomy and Microdiscectomy for 1 year after surgery

Study Arms (2)

Open discectomy

OTHER

This group of patients are treated by open discectomy

Procedure: Microdiscectomy

Microdiscectomy

OTHER

This group of patients are treated by Microdiscectomy

Procedure: Microdiscectomy

Interventions

Also known as: Open discectomy
MicrodiscectomyOpen discectomy

Eligibility Criteria

Age19 Years - 46 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Adults who are symptomatic lumbar disc herniation L4-5. Each patient was assessed clinically and MRI was done for all the patients to prove clinically, the symptomatic lumbar disc herniation which was present in all patients. Conservative treatment for 6weeks was failed

You may not qualify if:

  • smoking, previous lumbar spine surgery, Diabetes Melitus (DM) and neuromuscular disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Hamawandi SA, Sulaiman II, Al-Humairi AK. Open fenestration discectomy versus microscopic fenestration discectomy for lumbar disc herniation: a randomized controlled trial. BMC Musculoskelet Disord. 2020 Jun 15;21(1):384. doi: 10.1186/s12891-020-03396-x.

MeSH Terms

Conditions

Intervertebral Disc Displacement

Condition Hierarchy (Ancestors)

Spinal DiseasesBone DiseasesMusculoskeletal DiseasesHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant professor of orthopedic surgery

Study Record Dates

First Submitted

September 27, 2019

First Posted

October 2, 2019

Study Start

March 4, 2015

Primary Completion

August 15, 2019

Study Completion

August 20, 2019

Last Updated

May 11, 2020

Record last verified: 2020-05