NCT04107948

Brief Summary

Fibromyalgia affects 2 to 5% of adults in the general population. Patients describe a combination of symptoms centred around fatigue not induced by exercise and not relieved by rest. The diagnosis of fibromyalgia is self-perpetuating by the deconditioning, consequence of a reduced muscle mass due to inactivity and periods of prolonged rest. Thus, it seems fundamental to develop other non-drug approaches: among them, adapted physical activity is recommended by most learned societies because of a good level of evidence (Level 1, Grade A). The question remains, however, whether simple advice to resume physical activity is sufficient (routine care with medical assessment at 3 months) or whether a physical activity supervised inside and outside the hospital is not more relevant.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
330

participants targeted

Target at P75+ for not_applicable

Timeline
65mo left

Started Jan 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

7 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress54%
Jan 2020Oct 2031

First Submitted

Initial submission to the registry

September 26, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 27, 2019

Completed
4 months until next milestone

Study Start

First participant enrolled

January 23, 2020

Completed
5.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2031

Expected
Last Updated

May 6, 2026

Status Verified

May 1, 2026

Enrollment Period

5.7 years

First QC Date

September 26, 2019

Last Update Submit

May 5, 2026

Conditions

Keywords

sedentary timetherapeutic education sessions

Outcome Measures

Primary Outcomes (1)

  • physical activity

    Measure the durability of adherence/therapeutic compliance of fibromyalgia patients based on an objective measurement of physical activity: average measured from 7 days of actimetry, Actigraph

    12 months

Secondary Outcomes (20)

  • sedentary

    12 and 24 months

  • physical activity

    0, 1, 3, 6, 12 and 24 months

  • sedentary

    0, 1, 3, 6, 12 and 24 months

  • health status

    0, 1, 3, 6, 12 and 24 months

  • fatigue

    0, 1, 3, 6, 12 and 24 months

  • +15 more secondary outcomes

Study Arms (2)

fibromyalgia patients with physical activity program

EXPERIMENTAL

Two weekly exercise sessions at the university hospital of St-Etienne for 1 month then relay outside in a sports association or club certified "Sports Health" in the Loire (42) or Haute-Loire (43) for 2 months.

Other: physical activity program

fibromyalgia patients with physical activity at home

OTHER

Advice and recommendations of physical activity at home (= current clinical practice, from 1 to 3 sessions per week in autonomy).

Other: Advice and recommendations of physical activity at home

Interventions

Advice and recommendations of physical activity at home (= current clinical practice, from 1 to 3 sessions per week in autonomy).

fibromyalgia patients with physical activity at home

Two weekly exercise sessions at the university hospital of St-Etienne for 1 month then relay outside in a sports association or club certified "Sports Health" in the Loire (42), Haute-Loire (43) or Ardèche (07) for 2 months.

fibromyalgia patients with physical activity program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient diagnosed with fibromyalgia according to ACR (American College of rheumatology) criteria (total score WPI (Widespread Pain Index) + SS (Severity Scale) ) ≥ 13
  • French writing and speaking
  • Signature of informed consent

You may not qualify if:

  • Cardiac or respiratory diseases that contraindicate the practice of physical activity
  • Significant co-morbidities that contraindicate the practice of physical activity: associated cardiac pathologies (severe rhythm disorders such as rapid atrial fibrillation), respiratory pathologies (severe obstructive or severe respiratory insufficiency), disabling joint pathologies (knee osteoarthritis or osteoarthritis of the hip) training on a treadmill or on a high intensity bike).
  • Impossibility of submitting to the medical monitoring of the program for geographical, social or psychological reason

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

CH d'ANNONAY

Annonay, 07100, France

Location

CH de Firminy

Firminy, 42700, France

Location

CH de MONTBRISON

Montbrison, 42600, France

Location

CH de Rive de Gier

Rive-de-Gier, 42800, France

Location

CH de ROANNE

Roanne, 42300, France

Location

CH du Gier

Saint-Chamond, 42400, France

Location

Chu Saint Etienne

Saint-Etienne, 42055, France

Location

Related Publications (2)

  • Colas C, Jumel A, Vericel MP, Barth N, Manzanares J, Goutte J, Fontana L, Feasson L, Hupin D, Guyot J. Understanding Experiences of Fibromyalgia Patients Involved in the Fimouv Study During COVID-19 Lockdown. Front Psychol. 2021 Jul 20;12:645092. doi: 10.3389/fpsyg.2021.645092. eCollection 2021.

  • Colas C, Goutte J, Creac'h C, Fontana L, Vericel MP, Manzanares J, Peuriere M, Akrour M, Martin C, Presles E, Barth N, Guyot J, Garros M, Trombert B, Massoubre C, Roche F, Feasson L, Marotte H, Cathebras P, Hupin D. Efficiency of an Optimized Care Organization in Fibromyalgia Patients: The From Intent to Move (FIMOUV) Study Protocol of a Randomized Controlled Trial. Front Public Health. 2021 May 25;9:554291. doi: 10.3389/fpubh.2021.554291. eCollection 2021.

MeSH Terms

Conditions

FibromyalgiaMotor ActivitySedentary Behavior

Interventions

Counseling

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesBehavior

Intervention Hierarchy (Ancestors)

Mental Health ServicesBehavioral Disciplines and ActivitiesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • David HUPIN

    CHU de Saint Etienne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 26, 2019

First Posted

September 27, 2019

Study Start

January 23, 2020

Primary Completion

October 1, 2025

Study Completion (Estimated)

October 1, 2031

Last Updated

May 6, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations