Reconnecting: Improving Interoception to Reduce Suicidal Ideation in the Military

NCT04103385 | Completed

• 1 other identifier: G03177
• Study Type: interventional
• Target: 195
• Locations: 1 country
• Sites: 2

Brief Summary

Background: Interoception is defined as the "sense of the physiological condition of the entire body" and is crucial for recognizing emotions and sensations (e.g., hunger, temperature, pain) and responding accordingly. The investigator's lab has conducted several independent studies and two pilot studies that support the hypothesis that disrupted interoception leads one to be disconnected from the body, and thus more able to harm the body should one desire to do so. Research suggests that interoceptive deficits may not only differentiate those who are thinking about suicide from those who engage in suicidal behavior, but it may also provide information about who is at imminent risk for suicidal behavior. The identification of novel, short-term risk factors, like interoceptive deficits, allows for the development of new treatment applications for suicide, which is important for several reasons: 1) suicide rates have increased in recent years, especially among military populations, and 2) existing treatment approaches are often ineffective, lengthy, expensive, or impractical for large-scale dissemination. This project evaluates a novel, brief intervention for interoceptive deficits and suicidal behavior with the potential to be acceptable and feasible for a military population.

Conditions

Suicidal Ideation; Interoception

Keywords

interoception; suicidal ideation; suicide; military; intervention; clinical trial

Outcome Measures

Primary Outcomes (1)

• Multidimensional Assessment of Interoceptive Awareness

  This 35-item scale has 8 subscales that measure the ability to recognize and accurately identify emotions and physiological sensations.

  Within one week of completing the intervention. Also administered at one and three month follow-up.

Secondary Outcomes (1)

• Suicidal ideation

  Within one week of completing the intervention. Also administered at one and three month follow-up.

Other Outcomes (1)

• Body Functionality

  Within one week of completing the intervention. Also administered at one and three month follow-up.

Study Arms (2)

Reconnecting to Internal Sensations and Experiences

EXPERIMENTAL

Aims to improve "interoception" or connection to the body's emotions \& internal sensation and reduce suicidal ideation.

Behavioral: RISE (Reconnecting to Internal Sensations and Experiences)

Restoring Individual Strength and Energy

ACTIVE COMPARATOR

Aims to reduce life stressors and improve physical health

Behavioral: RISE (Reconnecting to Individual Strength and Energy)

Interventions

RISE (Reconnecting to Internal Sensations and Experiences) BEHAVIORAL

The overarching goal of RISE is to increase interoception by reconnecting people with their internal sensations

Reconnecting to Internal Sensations and Experiences

RISE (Reconnecting to Individual Strength and Energy) BEHAVIORAL

Aims to reduce life stressors and improve physical health

Restoring Individual Strength and Energy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being seen for behavioral health services at Wright-Patterson Medical Center (WPMC) or Madigan Army Medical Center (MAMC) for participants recruited at those sites only; other participants were recruited through online advertisement
• Active Duty Service Members (MAMC \& WPMC) and Veterans (online arm)
• Between the ages of 18-65
• English language fluency

You may not qualify if:

• Active psychosis or mania,
• Serious suicidal intent requiring hospitalization or immediate treatment.

Sponsors & Collaborators

• Miami University: lead
• Auburn University: collaborator

Study Sites (2)

Wright Patterson Medical Center

Dayton, Ohio, 45433, United States

Location

Madigan Army Medical Center

Tacoma, Washington, 98431, United States

Location

Related Publications (6)

• Craig AD. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci. 2002 Aug;3(8):655-66. doi: 10.1038/nrn894.

  PMID: 12154366 BACKGROUND

• Forrest LN, Smith AR, White RD, Joiner TE. (Dis)connected: An examination of interoception in individuals with suicidality. J Abnorm Psychol. 2015 Aug;124(3):754-63. doi: 10.1037/abn0000074.

  PMID: 26147323 BACKGROUND

• Smith A, Forrest L, Velkoff E. Out of touch: Interoceptive deficits are elevated in suicide attempters with eating disorders. Eat Disord. 2018 Jan-Feb;26(1):52-65. doi: 10.1080/10640266.2018.1418243.

  PMID: 29384458 BACKGROUND

• Guerra VS, Calhoun PS; Mid-Atlantic Mental Illness Research, Education and Clinical Center Workgroup. Examining the relation between posttraumatic stress disorder and suicidal ideation in an OEF/OIF veteran sample. J Anxiety Disord. 2011 Jan;25(1):12-8. doi: 10.1016/j.janxdis.2010.06.025. Epub 2010 Jul 7.

  PMID: 20709493 BACKGROUND

• Nademin E, Jobes DA, Pflanz SE, Jacoby AM, Ghahramanlou-Holloway M, Campise R, Joiner T, Wagner BM, Johnson L. An investigation of interpersonal-psychological variables in air force suicides: a controlled-comparison study. Arch Suicide Res. 2008;12(4):309-26. doi: 10.1080/13811110802324847.

  PMID: 18828034 BACKGROUND

• Shelef L, Levi-Belz Y, Fruchter E. Dissociation and acquired capability as facilitators of suicide ideation among soldiers. Crisis. 2014;35(6):388-97. doi: 10.1027/0227-5910/a000278.

  PMID: 25231854 BACKGROUND

MeSH Terms

Conditions

Suicidal Ideation; Suicide

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: We will attempt to mask care provider. The Investigators will be completely blind to condition assignment. Outcomes will be assessed via computer and thus will also be masked.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 19, 2019
• First Posted: September 25, 2019
• Study Start: June 1, 2020
• Primary Completion: November 22, 2021
• Study Completion: November 22, 2021
• Last Updated: April 25, 2022

Record last verified: 2022-04

Locations

US (2)