NCT04096079

Brief Summary

PEACE study retrospectively evaluate patients who suffered an out-hospital cardiac arrest (OHCA) and who underwent a coronary angiography, enrolled in the registry of the Province of Pavia (Italy), Ticino Region (Switzerland), Wien region (Austria) and Nicosia area (Cyprus) to comprehend the best timing for post-ROSC ECG acquisition in order to reduce the number of false positive and to select the best candidates for emergency coronary angiography.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2015

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 14, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 19, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

February 12, 2020

Status Verified

February 1, 2020

Enrollment Period

4 years

First QC Date

September 14, 2019

Last Update Submit

February 11, 2020

Conditions

Keywords

Out-Of-Hospital Cardiac Arrest, STEMI, coronary angiography, post-ROSC ECG

Outcome Measures

Primary Outcomes (2)

  • Primary endpoint - PCI

    To assess the number of patients requiring a coronary angioplasty in the presence of ST segment elevation according to the ROSC-ECG time

    Up to 14 days after OHCA (hospital discharge)

  • Primary endpoint - Time

    To identify the ROSC-ECG time associated to the lowest rate of false positive

    Up to 14 days after OHCA (hospital discharge)

Secondary Outcomes (2)

  • Secondary outcome - PCI in STEMI patients

    Up to 14 days after OHCA (hospital discharge)

  • Secondary outcome - PCI in BBB patients

    Up to 14 days after OHCA (hospital discharge)

Study Arms (1)

OHCA patients

Patients who suffered an out-of-hospital cardiac arrest between 2015 and 2018 in Province of Pavia (Italy), Ticino Region (Switzerland), Wien area (Austria) and Nicosia area (Cyprus) who underwent a coronary angiography.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

OHCA patients

You may qualify if:

  • All the patients older than 18 years old resuscitated from an out-of-hospital cardiac arrest with an available post-ROSC twelve leads ECG who underwent to a coronary angiography during hospital stay.

You may not qualify if:

  • From the present study are excluded all the patients with a non-medical aetiology of the cardiac arrest (trauma, drowning, electrocution, drug or abuse substance overdose, asphyxia)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Out-of-Hospital Cardiac ArrestMyocardial InfarctionST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Heart ArrestHeart DiseasesCardiovascular DiseasesMyocardial IschemiaVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

September 14, 2019

First Posted

September 19, 2019

Study Start

January 1, 2015

Primary Completion

December 31, 2018

Study Completion

December 31, 2019

Last Updated

February 12, 2020

Record last verified: 2020-02