NCT04092413

Brief Summary

Onychopathies constitute one of the major challenges faced by a dermatologist in terms of its early detection and diagnosis . Many disorders can affect the nails, including deformity and dystrophy, infections, and ingrown toenails. Infections can involve any part of the nail and may or may not change the nail's appearance. Most nail infections are fungal (onychomycosis), but bacterial and viral infections occur .

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
384

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2019

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 14, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 17, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

November 1, 2019

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

September 17, 2019

Status Verified

September 1, 2019

Enrollment Period

1 year

First QC Date

September 14, 2019

Last Update Submit

September 16, 2019

Conditions

Nail Diseases

Outcome Measures

Primary Outcomes (1)

  • Percentage of subclinical nail involvement in relevant skin diseases

    dermoscopic examination of the nails searching for subclinical nail manifestations of some skin diseases like psoriasis , atopy , lichen , bullous diseases and alopecia areata

    almost 6 months after start of the research

Interventions

DermoscopeDEVICE

It is a non invasive tool that permits the visualization of morphological features that are not visible to the naked eye thus representing a link between macroscopic dermatopathology .

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients attending the Dermatology clinic , Assiut University Hospitals, Assiut, Egypt, during a period of one year complaining of ( psoriasis,PRP, lichen planus, atopic dermatitis and auto immune bullous diseases) will be recruited in the study

You may qualify if:

  • \- Patients complaining of common skin diseases ( psoriasis, atopic dermatitis, alopecia, lichen planus, and bullous diseases)

You may not qualify if:

  • Patients who had gross visible nail changes will be excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (7)

  • Yadav TA, Khopkar US. Dermoscopy to Detect Signs of Subclinical Nail Involvement in Chronic Plaque Psoriasis: A Study of 68 Patients. Indian J Dermatol. 2015 May-Jun;60(3):272-5. doi: 10.4103/0019-5154.156377.

    PMID: 26120154BACKGROUND

  • Tunc SE, Ertam I, Pirildar T, Turk T, Ozturk M, Doganavsargil E. Nail changes in connective tissue diseases: do nail changes provide clues for the diagnosis? J Eur Acad Dermatol Venereol. 2007 Apr;21(4):497-503. doi: 10.1111/j.1468-3083.2006.02012.x.

    PMID: 17373977BACKGROUND

  • Nakamura RC, Costa MC. Dermatoscopic findings in the most frequent onychopathies: descriptive analysis of 500 cases. Int J Dermatol. 2012 Apr;51(4):483-5. doi: 10.1111/j.1365-4632.2010.04720.x. No abstract available.

    PMID: 22435443BACKGROUND

  • Lencastre A, Lamas A, Sa D, Tosti A. Onychoscopy. Clin Dermatol. 2013 Sep-Oct;31(5):587-93. doi: 10.1016/j.clindermatol.2013.06.016.

    PMID: 24079588BACKGROUND

  • Ronger S, Touzet S, Ligeron C, Balme B, Viallard AM, Barrut D, Colin C, Thomas L. Dermoscopic examination of nail pigmentation. Arch Dermatol. 2002 Oct;138(10):1327-33. doi: 10.1001/archderm.138.10.1327.

    PMID: 12374538BACKGROUND

  • Grover C, Jakhar D. Onychoscopy: A practical guide. Indian J Dermatol Venereol Leprol. 2017 Sep-Oct;83(5):536-549. doi: 10.4103/ijdvl.IJDVL_242_16.

    PMID: 28485306BACKGROUND

  • Jiaravuthisan MM, Sasseville D, Vender RB, Murphy F, Muhn CY. Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy. J Am Acad Dermatol. 2007 Jul;57(1):1-27. doi: 10.1016/j.jaad.2005.07.073.

    PMID: 17572277BACKGROUND

MeSH Terms

Conditions

Nail Diseases

Condition Hierarchy (Ancestors)

Skin DiseasesSkin and Connective Tissue Diseases

Central Study Contacts

Eman Riad, MDT

CONTACT

01005298992e_riad@yahoo.com

Yasmen Tawfeek, MDT

CONTACT

01006033331dr.yasminmostawfik@yahoo.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

September 14, 2019

First Posted

September 17, 2019

Study Start

November 1, 2019

Primary Completion

November 1, 2020

Study Completion

December 1, 2020

Last Updated

September 17, 2019

Record last verified: 2019-09