Prevalence and Burden of Bronchiectasis in Tuberculous Patients

NCT04085133 | Completed

• 1 other identifier: 12345817
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree

Conditions

Pulmonary Tuberculoses

Outcome Measures

Primary Outcomes (1)

• To study prevalence of bronchiectasis in TB patients by case per year.

  How many patients of TB will be diagnosed as abronchiectasis

  One year

Secondary Outcomes (1)

• To evaluate the burden of bronchiectasis in TB patients

  one year

Interventions

Gene Xpert Chest x ray and MSCT chest DIAGNOSTIC_TEST

Sputum sample for T.B will be done using gene expert device and chest xray and high resolution ct to evaluate bronchectasis

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Any tuberculosis patients admited to assuit university hospital and assuit chest hospital

You may qualify if:

• patients were diagnosed to have tuberculosis by sputum culture and gene x pert.
• patients were diagnosed to have bronchiectasis after lab and radiological examination as well as clinical score.
• patients diagnosed as bronchiectasis after history of tuberculosis or anti Tuberculosis treatment with positive or negative tuberculous culture in the time of research.

You may not qualify if:

• patients presented with other Pulmonary diseases. 2-Chronic liver and renal disease . 3- Lung cancer and tumors. 4- patients were previously diagnosed as bronchiectasis .

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut unviresty

Asyut, 71511, Egypt

Location

Biospecimen

Retention: SAMPLES WITH DNA

Sputum by gene xpert

MeSH Terms

Conditions

Tuberculosis, Pulmonary

Condition Hierarchy (Ancestors)

Tuberculosis; Mycobacterium Infections; Actinomycetales Infections; Gram-Positive Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 2 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DR.Ahmad Shaddad

Study Record Dates

• First Submitted: May 28, 2019
• First Posted: September 11, 2019
• Study Start: September 26, 2019
• Primary Completion: January 1, 2020
• Study Completion: April 1, 2020
• Last Updated: February 17, 2023

Record last verified: 2019-09

Locations

EG (1)