NCT04078620

Brief Summary

Drug drug interactions is frequent in critically ill patients due to polypharmacy, different drug groups and prolonged ICU or hospital stay

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 15, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 20, 2019

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 25, 2019

Completed
12 days until next milestone

First Posted

Study publicly available on registry

September 6, 2019

Completed
Last Updated

September 6, 2019

Status Verified

August 1, 2019

Enrollment Period

7 months

First QC Date

August 25, 2019

Last Update Submit

September 1, 2019

Conditions

Drug Interaction

Outcome Measures

Primary Outcomes (2)

  • Severity of Drug interactions by Lexicomp interactions application

    Lexicomp interactions classified As: A(no known interactions) B(no action needed) C(monitor therapy) D(consider therapy modification) X (avoid combination)

    6months period

  • Severity of Drug interactions by Medescape interactions checker:

    Interactions classified with Medescape interactions checker as :(contraindicated, serious use alternative, monitor closely,minor)

    6months period

Interventions

Survey for drug drug interactions on medscape and lexicomp applicationsDIAGNOSTIC_TEST

Survey for drug drug interactions on Medscape and Lexicomp interaction checker applications

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All patients admitted to Surgical ICUs, zagazig University Hospital

You may qualify if:

  • all patients admitted to Surgical ICUs for six months period

You may not qualify if:

  • less than one day admission to ICU,not completed data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Liza Elsayed Ali

Zagazig, Sharquia, 33735, Egypt

Location

Study Officials

  • Liza Shallouf

    Zagazig University

    PRINCIPAL INVESTIGATOR

  • Heba Matar

    Zagazig University

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle investigator

Study Record Dates

First Submitted

August 25, 2019

First Posted

September 6, 2019

Study Start

June 15, 2018

Primary Completion

January 15, 2019

Study Completion

April 20, 2019

Last Updated

September 6, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will share

All data could be shared

Shared Documents
STUDY PROTOCOL
Time Frame
For indefinite time
Access Criteria
Easy, direct information are available for other researchers

Locations

EG(1)