NCT04076514

Brief Summary

The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC). This study main goal is to investigate benefits of prophylactic central neck dissection in clinically node-negative papillary thyroid carcinoma.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 28, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 3, 2019

Completed
12 months until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2020

Completed
Last Updated

July 14, 2020

Status Verified

July 1, 2020

Enrollment Period

29 days

First QC Date

August 28, 2019

Last Update Submit

July 10, 2020

Conditions

Papillary Thyroid Cancer

Outcome Measures

Primary Outcomes (1)

  • the incidence metastatic lymph node in patients with clinically node-negative thyroid carcinoma who underwent total thyroidectomy with central neck dissection

    numbers of positive histopathological lymph node biopsies postoperative

    12 months

Study Arms (1)

patients with node negative papillary thyroid carcinoma

Procedure: central neck dissection

Interventions

central neck dissectionPROCEDURE

dissection of central cervical lymph node grope in low grade papillary thyroid cancer

patients with node negative papillary thyroid carcinoma

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with papillary thyroid carcinoma with clinically negative lymph node who undergo total thyroidectomy and central neck dissetion in assiut university hospital, department of general surgery.

You may qualify if:

  • patients with papillary thyroid cancer with clinically node negative.

You may not qualify if:

  • patients with clinical evidence of nodal metastases.
  • patients with a previous history of thyroidectomy.
  • patients with mixed-type papillary thyroid cancer.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ahmed Kamel

Asyut, Asyut Governorate, Egypt

RECRUITING

MeSH Terms

Conditions

Thyroid Cancer, Papillary

Condition Hierarchy (Ancestors)

Adenocarcinoma, PapillaryAdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsThyroid NeoplasmsEndocrine Gland NeoplasmsNeoplasms by SiteHead and Neck NeoplasmsEndocrine System DiseasesThyroid Diseases

Central Study Contacts

ahmed kamel ali

CONTACT

00201021259455ahmed01155@med.aun.edu.eg

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
resident

Study Record Dates

First Submitted

August 28, 2019

First Posted

September 3, 2019

Study Start

September 1, 2020

Primary Completion

September 30, 2020

Study Completion

November 1, 2020

Last Updated

July 14, 2020

Record last verified: 2020-07

Locations

EG(1)