NCT04073836

Brief Summary

To analyze the relationship between the early diagnosis of cerebral palsy with the risk factors of this pathology in moderate and late premature infants

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2019

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

August 21, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 29, 2019

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

August 29, 2019

Status Verified

August 1, 2019

Enrollment Period

3 years

First QC Date

August 21, 2019

Last Update Submit

August 27, 2019

Conditions

Outcome Measures

Primary Outcomes (8)

  • gestation weeks

    Premature birth week

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • weight

    measurement, World Health Organization percentile

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • size

    measurement, World Health Organization percentile

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • cranial perimeter

    measurement about head, World Health Organization percentile

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • Apgar

    Outcome about Apgar Test

    at birth of each preterm

  • Magnetic resonance imaging rating scale

    Outcome about Neuroimaging in preterms

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • general movements outcome

    Outcome about General Movements Assessment. Three outcomes about movement of preterm. Normal, Poor Repertoire and Cramped Synchronized

    From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks

  • PERI outcome

    Outcome about Perinatal Risk Scale Scale. Minimum score: 0. Maximum score: 51

    through study completion, an average of 18 months

Eligibility Criteria

Age32 Weeks - 36 Weeks
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Subjects who were born between the week 32 + 0 days and the week 36 + 6 days

You may qualify if:

  • Subjects who were born between the week 32 + 0 days and the week 36 + 6 days and who are admitted to the Hospital Nuestra Señora del Prado de Talavera de la Reina or the Hospital Virgen de la Salud de Toledo.

You may not qualify if:

  • Any type of pre and perinatal diagnostic neurological involvement.
  • Any type of pathology associated with prematurity.
  • Children who have prescribed any of the following medications (10):
  • Barbiturates
  • Antiepileptic
  • Indomethacin
  • Dexamethasone

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Javier Merino Andrés

Toledo, 45006, Spain

RECRUITING

MeSH Terms

Conditions

Premature BirthCerebral Palsy

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesBrain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Javier Merino Andrés, MsC

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
18 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2019

First Posted

August 29, 2019

Study Start

January 1, 2019

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

August 29, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations