NCT04068818

Brief Summary

This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess image quality of acquired biometry images of the eye

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
87

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 22, 2019

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

August 23, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 28, 2019

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 27, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 27, 2021

Completed
Last Updated

August 4, 2022

Status Verified

August 1, 2022

Enrollment Period

1.7 years

First QC Date

August 23, 2019

Last Update Submit

August 2, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Image quality

    Comparison of the B-Scan image quality between the ANTERION and the reference device

    30 days

  • Agreement in identification of abnormality

    Agreement in identification of abnormality from OCT B-Scan images between ANTERION and the reference device

    30 days

Secondary Outcomes (1)

  • Adverse Events

    1 day

Study Arms (2)

Eyes with normal anterior segment

Device: ANTERION

Eyes with anterior segment abnormalities

Device: ANTERION

Interventions

ANTERIONDEVICE

Biometry images will be acquired on the ANTERION and the reference device and the image quality and the identification of abnormalities will be assessed by a reading center

Eyes with anterior segment abnormalitiesEyes with normal anterior segment

Eligibility Criteria

Age22 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A: normal eyes B: eyes with anterior segment abnormalities

You may qualify if:

  • Age 22 years or older
  • Able and willing to undergo the test procedures, sign informed consent, and follow instructions
  • Able to fixate
  • With eye pathology status for each of the two eye populations. A. Eye with normal anterior segment
  • B. Eyes with anterior segment abnormalities identified with the slit lamp exam including but not limited to:
  • glaucoma surgeries: trabeculectomy, laser peripheral iridotomy and drainage devices
  • corneal surgeries: corneal inlays and corneal transplants
  • pterygium and corneal scar

You may not qualify if:

  • Subjects which were enrolled in the B-2018-1 Study
  • Physical inability to be properly positioned at the study devices or eye exam equipment
  • Contact lenses worn during imaging

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

State University of New York College of Optometry

New York, New York, 10036, United States

Location

MeSH Terms

Conditions

Eye Abnormalities

Condition Hierarchy (Ancestors)

Eye DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Mitchell Dul

    State University of New York College of Optometry

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 23, 2019

First Posted

August 28, 2019

Study Start

August 22, 2019

Primary Completion

April 27, 2021

Study Completion

April 27, 2021

Last Updated

August 4, 2022

Record last verified: 2022-08

Locations