Analysis of the Capnography Curve Can Allow the Discrimination of Obstructive Patients - Modeling the Capnography Curve

NCT04064580 | Unknown

• 1 other identifier: 7245
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Obstructive respiratory diseases such as asthma or COPD are a common reason for emergency room visits. Currently, nasal gill capnography and oxygen saturation measurement (SpO2) are the only two non-invasive means of continuously monitoring a respiratory pathology. To date, Respiratory Functional Explorations (CFE) and more particularly spirometry, are considered as the reference examinations for the diagnosis or monitoring of asthma or COPD. However, physical and physical constraints make their use almost impossible in the context of the emergency with patients presenting to emergencies in respiratory distress, often require oxygen therapy or even non-invasive ventilation. Only pulmonary auscultation can make the diagnosis of acute decompensation of obstructive pathology. This technique is qualitative and imprecise, sometimes leading to a diagnostic uncertainty resulting in delay in taking charge and inappropriate therapy. Studies have shown a change in the capnography curve in obstructive airway disorder and a strong correlation between some capnography parameters and spirometry parameters such as the Tiffeneau ratio (FEV1 / FVC), suggesting capnography as a simple and effective technique for the diagnosis of obstructive syndrome of patients in emergencies.

Conditions

Respiratory Pathology; Obstructive Syndrome

Keywords

capnography

Outcome Measures

Primary Outcomes (1)

• Spirometry measurement

  Tiffenau Report Compendium (FEV1 / FVC) and FEV1 for spirometry (gold standard defining presence of obstructive disorder). Collection of the capnography curves of each patient allowing in a second time to perform an analysis of the curve by different methods.

  1 day

Interventions

diagnostic test OTHER

performing a capnography examination

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major patient requiring spirometry breathing functional exploration

You may qualify if:

• Major patient male or female
• Patient with respiratory disease with and without obstructive syndrome or patient without respiratory pathology
• Patient requiring spirometry breathing functional exploration
• Subject affiliated to a social health insurance scheme
• Subject able to understand the objectives and the risks related to the research and to give its non opposition

You may not qualify if:

• Pregnant and lactating woman
• Patient not affiliated to a social protection scheme
• Impossibility of giving the subject information enlightened (subject in emergency situation, difficulties of understanding the subject, ...)
• Subject under the protection of justice Subject under guardianship or curatorship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 11, 2019
• First Posted: August 22, 2019
• Study Start: November 1, 2019
• Primary Completion: November 1, 2019
• Study Completion: July 1, 2021
• Last Updated: October 15, 2019

Record last verified: 2019-07

Locations

FR (1)