Short-bout Handgrip Exercise Intervention

NCT04059497 | Completed

• 1 other identifier: Handgrip pilot
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to examine the effect of practicing short-bout handgrip and isometric exercises on nicotine craving, smoking urges and withdrawal symptoms in adult smokers undergoing acute tobacco abstinence. The study is a randomized controlled trial to test the effect of practicing a set of short-bout exercises (10-second exercise) on reducing nicotine craving and withdrawals. Smokers, who have been abstinent from tobacco use for 9 hours, will join a guided exercise session using 10s-E or a healthy-diet (HD, control) intervention session, and complete a craving assessment before and 2 assessments after the respective intervention session. Primary outcomes will be nicotine craving, smoking urges and withdrawal symptoms.

Conditions

Smoking (Tobacco) Addiction

Keywords

Craving; Smoking urge; Withdrawal; Nicotine; Exercise; Isometric; Handgrip

Outcome Measures

Primary Outcomes (3)

• Nicotine craving

  How strong is your desire to smoke right now (Scale 1-7)

  Baseline, immediate after intervention, 15-minute follow-up

• Smoking urge

  10-item Questionnaire of Smoking Urges-Brief

  Baseline, immediate after intervention, 15-minute follow-up

• Withdrawal sysmptoms

  Mood and Physical Symptoms Scale

  Baseline, immediate after intervention, 15-minute follow-up

Study Arms (2)

Exercise group

EXPERIMENTAL

The exercise group will receive a 10-minute exercise intervention.

Behavioral: Exercise condition

Healthy diet group

EXPERIMENTAL

The healthy diet group (control) will receive a 10-minute healthy-diet intervention.

Behavioral: Healthy diet condition

Interventions

Exercise condition BEHAVIORAL

Each participant in the intervention group can freely choose a handgrip of strength from 10 to 25kg which can be gripped with adequate grip strength. The PI will play the short video (5 minutes, www.youtube.com/watch?v=mZex2Wwy3fU) about the 10s-E for the participant, including (1) rapid grip-and-release the handgrip for at least 30 times in 10seconds in each hand, and (2) short-bout hand pushing and pulling exercises without handgrip. During the video, participants are asked to follow the 10s-E demonstrated by the medical professor. After the video, the PI will guide the participant to repeat the 10s-E for 5 times within the next 5 minutes. If participants feel pain in their hands, they can slow down the exercise. Between each exercise set, rest time for 10-20 seconds will be allowed. After practicing all these exercises, participants are asked to complete a post-intervention questionnaire

Exercise group

Healthy diet condition BEHAVIORAL

The control group will watch two videos on healthy diet (https://www.youtube.com/watch?v=w\_u4BYV2Okc). Similar to the 10s-E condition, they will complete a post-intervention questionnaire after the two videos.

Healthy diet group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Consume 10+ traditional cigarettes a day
• Aged 18 years or above
• Able to communicate in Cantonese
• Self-reported no serious injury of hands and arms
• Self-reported no mental illnesses
• Before the intervention and assessment session, the invited participants will be assessed with the following eligibility criteria:
• Self-reported no smoking in past 9 hours before the intervention session
• Exhaled carbon monoxide \<= 15 parts per million (ppm) or reduced by at least 50% compared to that measured at recruitment stage

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

Tung Wah Group of Hospitals

Hong Kong, Hong Kong

Location

Related Publications (1)

• Zhang MJ, Cheung YTD, Wang Q, Cheng CCW, Luk TT, He WJ, Wang MP, Lam TH. Efficacy of simple and very brief handgrip and isometric exercises for reducing withdrawal symptoms in cigarette smokers: A pilot randomized controlled trial. Tob Induc Dis. 2024 May 24;22. doi: 10.18332/tid/187839. eCollection 2024.

  PMID: 38800350 DERIVED

MeSH Terms

Conditions

Smoking; Behavior, Addictive; Motor Activity

Condition Hierarchy (Ancestors)

Behavior; Compulsive Behavior; Impulsive Behavior

Study Officials

• Derek Cheung, PhD

  School of Nursing, HKU

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 12, 2019
• First Posted: August 16, 2019
• Study Start: September 15, 2019
• Primary Completion: January 31, 2020
• Study Completion: June 30, 2020
• Last Updated: November 4, 2020

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP

Locations

HK (1)