NCT04058769

Brief Summary

Aim of the project is the development of a software for implementation of anesthesiology guidelines in the preoperative evaluation. The software bases on the 2014 and 2018 guidelines of the European Society of Anesthesiology (ESA) for the pre-operative evaluation of adults undergoing non-cardiac surgery. Traditional premedication is compared with the new software-guided premedication by using a cross-over design. 200 patients are included in the study, 100 of which are first evaluated the traditional way and then with the software, 100 patients are treated the other way round. Results of the two premedication methods are compared according to the primary endpoint "correct approval for OP" and the secondary endpoints number of missed apparative examinations, number of unnecessary apparative examinations, time required for premedication, length of hospital stay, mortality and postoperative complications.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 8, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 16, 2019

Completed
1.7 years until next milestone

Study Start

First participant enrolled

May 1, 2021

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2022

Completed
Last Updated

October 19, 2022

Status Verified

March 1, 2022

Enrollment Period

1.2 years

First QC Date

August 8, 2019

Last Update Submit

October 18, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • correct approval for operation

    number of patients that were approved correctly for surgery

    1 day

Secondary Outcomes (5)

  • missing examinations

    1 day

  • unnecessary examinations

    1 day

  • mortality

    30 days

  • length of hospital stay

    30 days

  • postoperative complications

    30 days

Study Arms (2)

Software first

OTHER

Patients that are pre-operatively assessed first software-guided and then traditional

Device: Premedication Guide

Traditional

OTHER

Patients that are first pre-operatively assessed in the traditional way and then with aid of the software

Device: Premedication Guide

Interventions

Software with guidelines recommendations for preoperative assessment

Software firstTraditional

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \>= 18 years
  • ASA 3 or 4
  • elective surgery
  • written informed consent

You may not qualify if:

  • emergency surgery
  • patient not being able to give informed consent
  • non-german-speaking patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

TU Muenchen

Munich, 81675, Germany

Location

Related Publications (1)

  • Kagerbauer SM, Wissler J, Andonov DI, Ulm B, Schneider G, Podtschaske AH, Blobner M, Jungwirth B. Implementation of a software-based decision support tool for guideline-appropriate preoperative evaluation: a prospective agreement study. Br J Anaesth. 2024 Sep;133(3):519-529. doi: 10.1016/j.bja.2024.06.001. Epub 2024 Jul 5.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 8, 2019

First Posted

August 16, 2019

Study Start

May 1, 2021

Primary Completion

July 30, 2022

Study Completion

September 30, 2022

Last Updated

October 19, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations