An Urban Trail Network and Cardiovascular Disease: A Natural Experiment

NCT04057417 | Unknown

• 1 other identifier: HS20928
• Study Type: interventional
• Target: 225
• Locations: 1 country
• Sites: 1

Brief Summary

Associations between the built environment and health behaviours are robust, however (1) it remains unclear if the behaviours they elicit lead to meaningful improvements in health outcomes, at the population level and (2) little experimental evidence exists supporting these associations. The primary objective of this study is to capitalize on an urban natural experiment to determine if changing the built environment to support physical activity will (1) reduce the burden of CVD within a population and (2) if it's a cost-effective population intervention. An interrupted time series analysis will be performed over a period of 19 years to determine if the expansion of an urban trail network is associated with reductions in major advserse cardiovascular events (MACE) and CVD-related risk factors within a large urban centre in Canada.

Conditions

Cardiovascular Diseases; Cardiovascular Risk Factor; Diabetes Mellitus

Keywords

physical activity; built environment

Outcome Measures

Primary Outcomes (1)

• Major adverse cardiovascular events

  Seasonal incident rates of CVD-related mortality, new hospital admissions for cardiac-related events, valvular disease, ischemic heart disease and stroke

  10 years

Secondary Outcomes (1)

• Cardiovascular disease-related risk factors

  10 years

Other Outcomes (1)

• Trail counts

  12 months

Study Arms (2)

Urban Trail Expansion

EXPERIMENTAL

Neighbourhoods within 400m to 800m of a neely built greenway, defined as a multi-use concrete/asphalt trail that was \>4km in length)

Other: Urban Trail

Control

NO INTERVENTION

Neighbourhoods that are located beyond 400 to 800m of a newly built greenway

Interventions

Urban Trail OTHER

A newly built urban trail that was part of a large policy/infrastructure investment from the city/province to enhance the built environment for active transport and recreational physical activity in the city of Winnipeg, Manitoba Canada between 2010 and 2012.

Urban Trail Expansion

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The entire population of Winnipeg

You may not qualify if:

• Individuals \< 30 years of age and \>65 years of age.

Sponsors & Collaborators

• University of Manitoba: lead
• Unity Health Toronto: collaborator
• Ontario Agency for Health Protection and Promotion: collaborator
• University of Toronto: collaborator

Study Sites (1)

Children's Hospital Research Institute of Manitoba

Winnipeg, Manitoba, R3E 3P4, Canada

RECRUITING

Related Publications (2)

• McGavock J, Hobin E, Prior HJ, Swanson A, Smith BT, Booth GL, Russell K, Rosella L, Isaranuwatchai W, Whitehouse S, Brunton N, Burchill C. Multi-use physical activity trails in an urban setting and cardiovascular disease: a difference-in-differences analysis of a natural experiment in Winnipeg, Manitoba, Canada. Int J Behav Nutr Phys Act. 2022 Mar 28;19(1):34. doi: 10.1186/s12966-022-01279-z.

  PMID: 35346244 DERIVED

• Hobin E, Swanson A, Booth G, Russell K, Rosella LC, Smith BT, Manley E, Isaranuwatchai W, Whitehouse S, Brunton N, McGavock J. Physical activity trails in an urban setting and cardiovascular disease morbidity and mortality in Winnipeg, Manitoba, Canada: a study protocol for a natural experiment. BMJ Open. 2020 Feb 18;10(2):e036602. doi: 10.1136/bmjopen-2019-036602.

  PMID: 32075847 DERIVED

MeSH Terms

Conditions

Cardiovascular Diseases; Diabetes Mellitus; Motor Activity

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Natural Experiment

Study Record Dates

• First Submitted: January 29, 2019
• First Posted: August 15, 2019
• Study Start: January 5, 2018
• Primary Completion: December 1, 2019
• Study Completion: December 1, 2020
• Last Updated: August 15, 2019

Record last verified: 2019-08

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)