NCT04056585

Brief Summary

This study evaluates the addition of intermittent pneumatic compression maneuver to axillary brachial plexus block in forearm and hand surgery. Half of participants will receive axillary brachial plexus block and intermittent pneumatic compression maneuver, while the other half will receive only axillary brachial plexus block.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 15, 2019

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

August 9, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 14, 2019

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2020

Completed
Last Updated

August 14, 2019

Status Verified

August 1, 2019

Enrollment Period

1 year

First QC Date

August 9, 2019

Last Update Submit

August 13, 2019

Conditions

Keywords

brachial plexus blockintermittent pneumatic compression maneuver

Outcome Measures

Primary Outcomes (1)

  • Time to achieve complete sensory block

    Defined as the time to reach an absent sensation in the pinprick test at all four nerve distributions (ulnar nerve, radial nerve, median nerve, and musculocutaneous nerve)

    1 hour

Secondary Outcomes (1)

  • Time to achieve surgical anaesthesia

    1 hour

Study Arms (2)

Brachial plexus block with intermittent pneumatic compression

EXPERIMENTAL

Hand and forearm surgery is performed after axillary brachial plexus block with intermittent pneumatic compression for 3 minutes.

Procedure: Ultrasound guided axillary plexus blockProcedure: Intermittent pneumatic compression maneuver

Brachial plexus block

PLACEBO COMPARATOR

Hand and forearm surgery is performed after axillary brachial plexus block only.

Procedure: Ultrasound guided axillary plexus block

Interventions

Ultrasound guided axillary plexus block with 1.5% mepivacaine 30 ml

Brachial plexus blockBrachial plexus block with intermittent pneumatic compression

Following ultrasound guided axillary plexus block, the pneumatic compression maneuver of upper arm is composed of 6 repeated inflation-deflation periods; inflation with a pressure of 200 mmHg for 30 seconds and deflation for 10 seconds each.

Brachial plexus block with intermittent pneumatic compression

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • adults between ages of 20 and 50
  • patients who are scheduled forearm and hand surgery with axillary brachial plexus block
  • American Society of Anesthesiologists Physical Status classification 1 or 2
  • patients who voluntarily agree to participate in the trial

You may not qualify if:

  • patients who are pregnant or lactating
  • patient who does not agree to participate in the study
  • patient with side effects on local anesthetics
  • patient with neurologic deficit of upper arm
  • patients with comorbidities of cardiac, pulmonary, renal, cerebral, and hepatic systems
  • patients with peripheral vascular disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

International St. Mary's Hospital

Incheon, 22711, South Korea

RECRUITING

MeSH Terms

Conditions

Forearm InjuriesHand Injuries

Condition Hierarchy (Ancestors)

Arm InjuriesWounds and Injuries

Central Study Contacts

Hye-Won Jeong, master degree

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

August 9, 2019

First Posted

August 14, 2019

Study Start

July 15, 2019

Primary Completion

July 15, 2020

Study Completion

October 15, 2020

Last Updated

August 14, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations