NCT04049526

Brief Summary

AIM: to investigate the influence of different music genres on Heart Rate Variability (HRV) of preterm infants. Neonates undergo a daily randomized music listening program. An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 6, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 8, 2019

Completed
Last Updated

August 9, 2019

Status Verified

August 1, 2019

Enrollment Period

5 months

First QC Date

August 6, 2019

Last Update Submit

August 8, 2019

Conditions

Keywords

MusicPreterm infantsHeart Rate Variability

Outcome Measures

Primary Outcomes (1)

  • Heart Rate Variability (HRV) variation in preterm infants according to different music genres listening

    An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.

    Enrollment performed when sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the treatment

Interventions

Neonates undergo a daily randomized music listening program (25 minutes, every day, for 3 days) based on different music genres listening (soft pop-rap, pop-rock and classical music). Music programs is followed by 1 day of no music monitoring (25 minutes). An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure

Eligibility Criteria

Age1 Day - 90 Days
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Enrollment performed when sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the test

You may qualify if:

  • gestational age between the 23th and the 32nd week
  • birth weight \<1500g
  • appropriate for gestational age, sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the test

You may not qualify if:

  • genetic anomalies, chromosomal aberrations, congenital heart malformations, intraventricular haemorrhage (\> grade II on ultrasound), periventricular Leukomalacia
  • neonates with failed responses to bilateral hearing screening performed by Automated Auditory Brainstem Response testing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Barbara Sgobbi

Varese, Italy

Location

MeSH Terms

Conditions

Infant Behavior

Condition Hierarchy (Ancestors)

Child BehaviorBehavior

Study Officials

  • Barbara Sgobbi

    Tincontro Onlus

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Musicotherapist

Study Record Dates

First Submitted

August 6, 2019

First Posted

August 8, 2019

Study Start

February 1, 2019

Primary Completion

June 30, 2019

Study Completion

June 30, 2019

Last Updated

August 9, 2019

Record last verified: 2019-08

Locations