NCT04048798

Brief Summary

High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air. Group I patients will be applied HFNC before and after bariatric surgery, Group II patients will be applied a constant O2 concentration via face mask. Oxygen pressure, oxygen saturation, carbon dioxide, respiration frequency, forced vital capacity will be measured before and after surgery.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
112

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 2, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 7, 2019

Completed
5 months until next milestone

Study Start

First participant enrolled

January 1, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2021

Completed
Last Updated

August 7, 2019

Status Verified

August 1, 2019

Enrollment Period

1 year

First QC Date

August 2, 2019

Last Update Submit

August 6, 2019

Conditions

Keywords

morbid obesitybariatric surgeryhigh frequency nasal cannulaoxygenation

Outcome Measures

Primary Outcomes (2)

  • PO2 value

    PO2 value will be measured before HFNC or face mask, after HFNC or face mask and after surgery

    24 hours

  • PCO2 value

    PO2 value will be measured before HFNC or face mask, after HFNC or face mask and after surgery

    24 hours

Study Arms (2)

Oxygen therapy via HFNC

ACTIVE COMPARATOR

Patients who will be applied high frequency nasal cannula before and after surgery

Other: Oxygen therapy via HFNC

Oxygen therapy via face mask

ACTIVE COMPARATOR

Patients who will be applied O2 via face mask before and after surgery

Other: Oxygen therapy via face mask

Interventions

Oxygen treatment will be applied to the patients via HFNC before and after surgery

Oxygen therapy via HFNC

Oxygen treatment will be applied to the patients via face mask before and after surgery

Oxygen therapy via face mask

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with a body mass index of 40-55 kg/m2
  • American Society of Anesthesiologists score II-III
  • Patients undergoing laparoscopic sleeve gastrectomy or one anastomosis gastric bypass

You may not qualify if:

  • Obstructive sleep apnea syndrome
  • Using a non invasive mechanical ventilation device preoperatively
  • Patients whoo will predicted to postanesthesia care unit admission postoperatively

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Baraka AS, Taha SK, Siddik-Sayyid SM, Kanazi GE, El-Khatib MF, Dagher CM, Chehade JM, Abdallah FW, Hajj RE. Supplementation of pre-oxygenation in morbidly obese patients using nasopharyngeal oxygen insufflation. Anaesthesia. 2007 Aug;62(8):769-73. doi: 10.1111/j.1365-2044.2007.05104.x.

    PMID: 17635423BACKGROUND

MeSH Terms

Conditions

Obesity, Morbid

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Cigdem A BEYOGLU

    İstanbul Üniversitesi- Cerrahpaşa Cerrahpaşa Tıp Fakültesi

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 2, 2019

First Posted

August 7, 2019

Study Start

January 1, 2020

Primary Completion

January 1, 2021

Study Completion

February 1, 2021

Last Updated

August 7, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

I am unaware of the advantages or disadvantages of sharing IPD