A Study to Determine the Tissue Properties, Vascular Physiology and Biochemical Milieu of Myofascial Trigger Points

NCT04045457 | Completed

• 2 other identifiers: PR00005701R01AR057348
• Study Type: interventional
• Target: 85
• Locations: 0 countries
• Sites: N/A

Brief Summary

Determine the effect of dry needling using a 32 gauge needle on active trigger points in subjects with chronic myofascial pain. Participants will receive treatment for active trigger points (3 on successive weeks) and will have pain, status of the trigger point and functional measures assessed at baseline, after treatment and eight weeks later.

Conditions

Myofascial Pain

Keywords

active trigger points

Outcome Measures

Primary Outcomes (3)

• Verbal Analog Scale

  scale of 0-10 as a measure of pain severity

  change from baseline to 3 weeks and at 8 weeks

• Presence of myofascial trigger point

  Digital palpation of the trigger point was performed by investigators and scored as present or absent; if present was it associated with spontaneous pain or was pain induced with palpation

  change from baseline to 3 weeks and at 8 weeks

• Brief Pain Inventory

  Validated scale of pain severity and interference

  change from baseline to 3 weeks and at 8 weeks

Secondary Outcomes (5)

• Oswestry Disability Scale

  change from baseline to 3 weeks and at 8 weeks

• MOS-short form 36 v2

  change from baseline to 3 weeks and at 8 weeks

• Manual Muscle test

  change from baseline to 3 weeks and at 8 weeks

• Profile of Mood States

  change from baseline to 3 weeks and at 8 weeks

• range of motion

  change from baseline to 3 weeks and at 8 weeks

Study Arms (1)

SIngle arm

OTHER

Single arm, intervention All recipients were treated with dry needling technique into active myofascial trigger points They received 1 treatment weekly for three weeks.

Procedure: dry needling

Interventions

dry needling PROCEDURE

insertion of needle into active myofascial trigger point

SIngle arm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• spontaneous soft tissue pain in shoulder and neck region

You may not qualify if:

• recent fracture, neurological injury or history of stroke, use of opioids

Sponsors & Collaborators

• George Mason University: lead
• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): collaborator

Related Publications (4)

• Turo D, Otto P, Hossain M, Gebreab T, Armstrong K, Rosenberger WF, Shao H, Shah JP, Gerber LH, Sikdar S. Novel Use of Ultrasound Elastography to Quantify Muscle Tissue Changes After Dry Needling of Myofascial Trigger Points in Patients With Chronic Myofascial Pain. J Ultrasound Med. 2015 Dec;34(12):2149-61. doi: 10.7863/ultra.14.08033. Epub 2015 Oct 21.

  PMID: 26491094 RESULT

• Gerber LH, Shah J, Rosenberger W, Armstrong K, Turo D, Otto P, Heimur J, Thaker N, Sikdar S. Dry Needling Alters Trigger Points in the Upper Trapezius Muscle and Reduces Pain in Subjects With Chronic Myofascial Pain. PM R. 2015 Jul;7(7):711-718. doi: 10.1016/j.pmrj.2015.01.020. Epub 2015 Feb 4.

  PMID: 25661462 RESULT

• Gerber LH, Sikdar S, Armstrong K, Diao G, Heimur J, Kopecky J, Turo D, Otto P, Gebreab T, Shah J. A systematic comparison between subjects with no pain and pain associated with active myofascial trigger points. PM R. 2013 Nov;5(11):931-8. doi: 10.1016/j.pmrj.2013.06.006. Epub 2013 Jun 28.

  PMID: 23810811 RESULT

• Turo D, Otto P, Shah JP, Heimur J, Gebreab T, Zaazhoa M, Armstrong K, Gerber LH, Sikdar S. Ultrasonic characterization of the upper trapezius muscle in patients with chronic neck pain. Ultrason Imaging. 2013 Apr;35(2):173-87. doi: 10.1177/0161734612472408.

  PMID: 23493615 RESULT

MeSH Terms

Interventions

Dry Needling

Intervention Hierarchy (Ancestors)

Complementary Therapies; Therapeutics; Physical Therapy Modalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 10, 2016
• First Posted: August 5, 2019
• Study Start: August 1, 2010
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: August 5, 2019

Record last verified: 2019-08