NCT04044157

Brief Summary

This study investigates cardiac output in young children under 18 months of age during the perioperative period by means of electrical cardiometry.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 31, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 5, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

September 23, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 17, 2020

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 19, 2020

Completed
Last Updated

December 21, 2020

Status Verified

December 1, 2020

Enrollment Period

6 months

First QC Date

July 31, 2019

Last Update Submit

December 18, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cardiac output

    Cardiac output will be non-invasivaly measured during the perioperative period by means of electrical electrocardiometry

    Measurements start before the induction of anesthesia and ends at emergence from anesthesia

Secondary Outcomes (3)

  • Association between cardiac output and blood pressure during anesthesia

    Time-locked measurements start before the induction of anesthesia and ends at emergence from anesthesia

  • Association between cardiac output and cerebral NIRS during anesthesia

    Time-locked measurements start before the induction of anesthesia and ends at emergence from anesthesia

  • Association between cardiac output and other anesthesia factors (concentration of anesthetic agent, carbon dioxide) during anesthesia

    Time-locked measurements start before the induction of anesthesia and ends at emergence from anesthesia

Interventions

cardiac output will be non-invasivaly measured by means of electrical cardiometry

Also known as: no other intervention

Eligibility Criteria

AgeUp to 17 Months
Sexall
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children under 18 months undergoing elective surgery lasting more than 30 minutes.

You may qualify if:

  • age 0 to 17 months included
  • undergo general anesthesia for surgery that is expected to last more than 30 minutes (combines anesthesia and surgical time)
  • parental/guardian permission (informed consent) obtained
  • ASA 1-3 status

You may not qualify if:

  • structural/anatomical anomaly or other circumstances (e.g. patient positioning) making it difficult to apply the sensors to the body
  • history of congenital heart diseases
  • known allergy to electrodes' glue
  • emergency surgery
  • prematurity (born before 37 week PMA)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospitals of Geneva

Geneva, 1205, Switzerland

Location

MeSH Terms

Conditions

Hypotension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Laszlo Vutskits, MD PhD

    University Hosptials of Geneva

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Head of Pediatric Anesthesia

Study Record Dates

First Submitted

July 31, 2019

First Posted

August 5, 2019

Study Start

September 23, 2019

Primary Completion

March 17, 2020

Study Completion

March 19, 2020

Last Updated

December 21, 2020

Record last verified: 2020-12

Locations