Concurrent Transcranial Direct Current Stimulation and Gait Training in Parkinson's Disease
The Effect of Concurrent Transcranial Direct Current Stimulation and Gait Training on Gait Performance When Doing the Cognitive Dual-task in People With Parkinson's Disease
1 other identifier
interventional
30
0 countries
N/A
Brief Summary
To investigate the effect of concurrent transcranial direct current stimulation and gait training on gait performance when doing the cognitive dual-task in people with Parkinson's Disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2019
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 31, 2019
CompletedFirst Posted
Study publicly available on registry
August 1, 2019
CompletedStudy Start
First participant enrolled
August 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2020
CompletedAugust 6, 2019
August 1, 2019
1.1 years
July 31, 2019
August 2, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Dual-task walking performance
To evaluate gait parameters while doing dual-task walking
Change from baseline at 4 weeks
Secondary Outcomes (4)
Single walking performance
Change from baseline at 4 weeks
Trail-making test A & B
Change from baseline at 4 weeks
Stroop color and word test-Chinese version
Change from baseline at 4 weeks
Digit span test
Change from baseline at 4 weeks
Study Arms (2)
Active tDCS plus gait training group
EXPERIMENTALParticipants in Active tDCS plus gait training group will execute Active tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.
Sham tDCS plus gait training group
SHAM COMPARATORParticipants in Sham tDCS plus gait training group will executeSham tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.
Interventions
Participants in experimental group will accept Active tDCS which combined with treadmill
Participants in control group will accept Sham tDCS which combined with treadmill
Eligibility Criteria
You may qualify if:
- Diagnosed with idiopathic PD
- Hoehn and Yahr stages I-III
- Mini Mental Status Examination (MMSE) score ≧ 24
- Could walk 10m independently with or without gait aid
You may not qualify if:
- Concurrent medication likely to affect mental performance
- tDCS contraindication
- Significant neurological, vestibular, visual disorders or psychiatric illness
- Musculoskeletal or cardiopulmonary disease
- Sensory system pathology
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
July 31, 2019
First Posted
August 1, 2019
Study Start
August 1, 2019
Primary Completion
August 31, 2020
Study Completion
August 31, 2020
Last Updated
August 6, 2019
Record last verified: 2019-08