NCT04041466

Brief Summary

The proposed clinical study aims at validating the diagnostic performance, in comparison with a reference ECG, of Withings HWA08 watch for the automatic identification of atrial fibrillation (AF).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
140

participants targeted

Target at P50-P75 for not_applicable atrial-fibrillation

Timeline
Completed

Started Jun 2019

Shorter than P25 for not_applicable atrial-fibrillation

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 7, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 12, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 12, 2019

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

July 31, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 1, 2019

Completed
Last Updated

August 5, 2019

Status Verified

August 1, 2019

Enrollment Period

1 month

First QC Date

July 31, 2019

Last Update Submit

August 2, 2019

Conditions

Keywords

Atrial FibrillationArrhythmias, CardiacCardiovascular diseasesHeart diseasesWearable Electronic DevicesElectrocardiography

Outcome Measures

Primary Outcomes (1)

  • AF and SR classification accuracy

    sensitivity and specificity of detection of AF and SR from 1-lead ECG against reference 12-lead ECG

    1 visit (30 minutes)

Secondary Outcomes (2)

  • Quality of the 1-lead ECG strips

    1 visit (30 minutes)

  • safety evaluation

    1 visit (30 minutes)

Study Arms (3)

Atrial fibrillation (AF)

EXPERIMENTAL

Patients diagnosed with AF during reference ECG

Diagnostic Test: AF detection by ECG

Sinus Rhythm (SR)

EXPERIMENTAL

Patients diagnosed with SR during reference ECG

Diagnostic Test: AF detection by ECG

Other Arrythmia

EXPERIMENTAL

Patients diagnosed with an arrhythmia other than AF during the reference ECG

Diagnostic Test: AF detection by ECG

Interventions

AF detection by ECGDIAGNOSTIC_TEST

Single-lead ECG with Withings watch HWA08 and reference 12-lead ECG

Atrial fibrillation (AF)Other ArrythmiaSinus Rhythm (SR)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adults, men or women, at least 18 years old
  • person having signed the informed consent form
  • person affiliated to a social security system

You may not qualify if:

  • vulnerable subject according to current regulation:
  • pregnant woman, parturient or breastfeeding
  • subject deprived of freedom by judicial, medical or administrative decision
  • subject legally protected or unable to express his consent
  • subject non-beneficiary of healthcare
  • subject falling into more than one of the above categories
  • subject who refused to participate in the study
  • subject in linguistic or psychic incapacity to sign a written informed consent form
  • subject in physical incapacity to wear a watch on their wrist
  • subject with electrical stimulation by pacemaker

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Clinique AXIUM Centre de cardiologie

Aix-en-Provence, 13090, France

Location

Centre Cardiologique du Nord

Saint-Denis, 93200, France

Location

MeSH Terms

Conditions

Atrial FibrillationArrhythmias, CardiacCardiovascular DiseasesHeart Diseases

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 31, 2019

First Posted

August 1, 2019

Study Start

June 7, 2019

Primary Completion

July 12, 2019

Study Completion

July 12, 2019

Last Updated

August 5, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations