NCT04038528

Brief Summary

The aim of this study is to understand, in adult patients with Type 2 diabetes mellitus, if the use of telemedicine (monitoring and treatment without patients having to attend a healthcare facility) and home-based care is more effective than traditional general practitioner (GP) and outpatient care in terms of patients taking medication regularly and their quality of life. The hypothesis of this study is that patients with Type 2 diabetes mellitus uploading data on a telemedicine system achieve a glycemic control, evaluated in terms of glycated hemoglobin levels, similar to that of patients followed in a traditional diabetes outpatient department, with improvements to quality of life

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
350

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2018

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2018

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

July 23, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 31, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2020

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2020

Completed
Last Updated

July 31, 2019

Status Verified

July 1, 2019

Enrollment Period

2 years

First QC Date

July 23, 2019

Last Update Submit

July 26, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • glycated hemoglobin (GlyH) level

    Level of glycated hemoglobin (GlyH) at the end of the study (18 months) in patients followed with telemedicine and in the control group when compared to baseline, with normal GlyH defined as \<5.6%.

    18 months

Secondary Outcomes (9)

  • Quality of life perception

    18 months

  • Body mass index (BMI)

    18 months

  • Abdominal circumference

    18 months

  • Triglyceride

    18 months

  • LDL-cholesterol

    18 months

  • +4 more secondary outcomes

Study Arms (2)

Telemedicine Group

Patients in this group monitor blood sugar levels at home and upload their data through a telemedicine systems.

Behavioral: telemonitoring of T2DM

Control Group

The control group will attend their routine appointments scheduled by their GPs and specialists in outpatient clinics and will record blood sugar levels according to the traditional method as per GP or specialist physician's indications.

Interventions

Baseline record of: * Weight * Height * BMI * Abdominal circumference * Winsor Index * ECG * Retinography * Blood level of (fasting values): total cholesterol, HDL cholesterol, LDL cholesterol, blood sugar, triglycerides, glycated hemoglobin These parameters will be checked again at 3, 6 and 18 months in the two groups. Telemedicine group (intervention): * Blood sugar (two measurements per week). * Body weight (weekly) * Blood pressure (weekly) Use of devices that allow the automatic upload of data via wi-fi or web is allowed Control group (control): Routine appointments scheduled by their GPs and specialists in outpatient clinics to record blood sugar levels as per standard GP or specialist physician's indications. Blood sugar level is measured in mg/dl in a drop of capillary blood with the use of standard glucose meter

Telemedicine Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adult patients with type 2 diabetes mellitus (T2DM) with diagnosis of DM made at least 1 year before the start of the study

You may qualify if:

  • Patients with type 2 diabetes mellitus (T2DM)
  • Diagnosis of DM made at least 1 year before the start of the study
  • Hypoglycemic treatment remained the same in the 3 months preceding the start of the study

You may not qualify if:

  • Diabetes other than T2DM
  • Pregnant women
  • Chronic conditions other than T2DM
  • Unable to give informed consent
  • Dementia or psychiatric conditions that can affect a person's will or ability to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ASP Catanzaro

Catanzaro, 88100, Italy

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Antonio V Gaddi, MD, PhD

    EuroGenLab, Bologna, Italy

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 23, 2019

First Posted

July 31, 2019

Study Start

March 1, 2018

Primary Completion

March 1, 2020

Study Completion

July 31, 2020

Last Updated

July 31, 2019

Record last verified: 2019-07

Data Sharing

IPD Sharing
Will share

The datasets generated during and/or analysed during the current study will be available upon request from DIGITCAL (digitcal01@gmail.com). Anonymised data will be made available to recognised research institutions for research purposes. Written request is required, and data will be shared after approval of the scientific and ethical committees of DIGITCAL. Criteria for data sharing are under discussion at the moment.

Time Frame
Not decided yet
Access Criteria
Not decided yet

Locations