NCT04036123

Brief Summary

Comparison of water-perfused (WP) and air-charged (AC) catheters for invasive urodynamic investigation (UDI) regarding consistency, features and artifacts.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 19, 2019

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 29, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

October 1, 2019

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2023

Completed
Last Updated

April 13, 2023

Status Verified

April 1, 2023

Enrollment Period

3.5 years

First QC Date

July 19, 2019

Last Update Submit

April 12, 2023

Conditions

Keywords

Urodynamic investigationLower urinary tract dysfunctionWater-perfused catheterAir-charged catheter

Outcome Measures

Primary Outcomes (1)

  • Interchangeability of the measurement method (air-charged vs. water-perfused measurement system) regarding the urodynamic observations, diagnostic result and subsequent treatment

    Once during urodynamic investigation

Secondary Outcomes (3)

  • Pressure changes during urodynamics using an air-charged vs. water-perfused measurement system

    Once during urodynamic investigation

  • Changes in bladder compliance [mL/cmH2O] during urodynamics using an air-charged vs. water-perfused measurement system

    Once during urodynamic investigation]

  • Incidence of side effects: number and intensity/severity (mild/moderate/severe) of AEs and SAE for the following categories during and for 7 days after the urodynamic investigation

    Once during urodynamic investigation and 7 days thereafter

Study Arms (1)

Urodynamic investigation

EXPERIMENTAL

Simultaneous UDI (same session repeat filling cystometry and pressure flow study) with an air-charged and water-perfused measurement system.

Other: Urodynamic investigation

Interventions

Simultaneous UDI (same session repeat filling cystometry and pressure flow study) with an air-charged and water-perfused measurement system.

Urodynamic investigation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male and female patients
  • Age ≥18 years
  • Informed consent
  • LUTD due to a neurological disorder
  • Competent German language skills

You may not qualify if:

  • Age \<18 years
  • Pregnancy or breast feeding (see chapter 3.6.)
  • Symptomatic UTI
  • Individuals especially in need of protection
  • No informed consent
  • Patients incapable to follow the trial, e.g. because of language problems, psychiatric disorders, dementia and so on.
  • Earlier participation in this clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Balgrist University Hospital

Zurich, Switzerland

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 19, 2019

First Posted

July 29, 2019

Study Start

October 1, 2019

Primary Completion

March 31, 2023

Study Completion

March 31, 2023

Last Updated

April 13, 2023

Record last verified: 2023-04

Locations